微小根霉作为新冠病毒感染患者毛霉病的病原体
Rhizopus microsporus as Causative Agent of Mucormycosis in COVID-19 Patient.
作者信息
Sedaghatalab Moslem, Nouripour-Sisakht Sadegh, Cheraghzadeh Seyed R, Sabz Gholamabas, Gharaghani Maral
出版信息
Clin Lab. 2022 Dec 1;68(12). doi: 10.7754/Clin.Lab.2022.220232.
BACKGROUND
The pandemic of coronavirus disease (COVID-19) emerged as a fatal infection, especially in immunocompromised patients. Currently, this infection is managed with systemic corticosteroids. Co-infection of CO-VID-19 with opportunistic fungi is increasingly recognized.
METHODS
We describe a case of rhino-cerebral mucormycosis 12 days following severe COVID-19 in a diabetic patient.
RESULTS
He received 50 mg amphotericin B and surgical debridement. The patient's symptoms improved following medical and surgical intervention.
CONCLUSIONS
Mucormycosis is an uncommon but serious infection that complicates the course of severe COVID-19. Subjects with diabetes mellitus and multiple risk factors may be at a higher risk for developing mucormycosis.
背景
冠状病毒病（COVID-19）大流行已成为一种致命感染，尤其是在免疫功能低下的患者中。目前，这种感染采用全身用皮质类固醇进行治疗。COVID-19与机会性真菌的合并感染越来越受到关注。
方法
我们描述了1例糖尿病患者在患重症COVID-19 12天后发生鼻脑型毛霉菌病的病例。
结果
他接受了50mg两性霉素B治疗及手术清创。经过药物和手术干预，患者症状有所改善。
结论
毛霉菌病是一种罕见但严重的感染，会使重症COVID-19的病程复杂化。患有糖尿病和多种危险因素的患者发生毛霉菌病的风险可能更高。
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