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本文引用的文献

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Slow versus fast subcutaneous heparin injections for prevention of bruising and site pain intensity.皮下缓慢注射肝素与快速注射肝素预防瘀斑和注射部位疼痛强度的比较。
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2
Influence of low-molecular-weight heparin injection sites on local bruising and pain: A systematic review and meta-analysis.低分子肝素注射部位对局部瘀斑和疼痛的影响:系统评价和荟萃分析。
J Clin Pharm Ther. 2021 Jun;46(3):688-697. doi: 10.1111/jcpt.13323. Epub 2020 Dec 15.
3
Effect of Cold Application on Bruising and Pain Following Heparin Subcutaneous Injection: A Systematic Review and Meta-Analysis.冷敷对皮下注射肝素后瘀斑和疼痛的影响:系统评价和荟萃分析。
J Nurs Scholarsh. 2020 Nov;52(6):634-642. doi: 10.1111/jnu.12598. Epub 2020 Sep 4.
4
Effectiveness of mechano-analgesia and cold application on ecchymosis, pain, and patient satisfaction associated with subcutaneous heparin injection.机械镇痛和冷敷对皮下肝素注射引起的瘀斑、疼痛和患者满意度的效果。
J Vasc Nurs. 2020 Jun;38(2):76-82. doi: 10.1016/j.jvn.2020.02.002. Epub 2020 Apr 16.
5
Effect of Cold Application on Pain and Bruising in Patients With Subcutaneous Injection of Low-Molecular-Weight Heparin: A Meta-Analysis.冷敷对皮下注射低分子肝素患者疼痛和瘀斑的影响:一项荟萃分析。
Clin Appl Thromb Hemost. 2020 Jan-Dec;26:1076029620905349. doi: 10.1177/1076029620905349.
6
The sensory and affective components of pain: are they differentially modifiable dimensions or inseparable aspects of a unitary experience? A systematic review.疼痛的感觉和情感成分:它们是可差异化调节的维度,还是单一体验的不可分割方面?系统评价。
Br J Anaesth. 2019 Aug;123(2):e263-e272. doi: 10.1016/j.bja.2019.03.033. Epub 2019 May 1.
7
The Effect of Extended Injection of Subcutaneous Heparin on Pain Intensity and Bruising Incidence.皮下肝素延长注射对疼痛强度和瘀伤发生率的影响。
Electron Physician. 2016 Jul 25;8(7):2650-4. doi: 10.19082/2650. eCollection 2016 Jul.
8
Spirituality and Religion in Pain and Pain Management.疼痛与疼痛管理中的精神性与宗教信仰
Health Psychol Res. 2013 Sep 23;1(3):e29. doi: 10.4081/hpr.2013.e29. eCollection 2013 Sep 24.
9
Assessment of four different methods in subcutaneous heparin applications with regard to causing bruise and pain.关于皮下注射肝素时导致瘀伤和疼痛情况的四种不同方法的评估。
Int J Nurs Pract. 2013 Aug;19(4):402-8. doi: 10.1111/ijn.12079. Epub 2013 Jun 14.
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The effect of injection duration and injection site on pain and bruising of subcutaneous injection of heparin.注射持续时间和注射部位对皮下注射肝素时疼痛和瘀伤的影响。
J Clin Nurs. 2014 Apr;23(7-8):1105-13. doi: 10.1111/jocn.12291. Epub 2013 Jul 12.

皮肤光型对接受依诺肝素治疗患者疼痛感知水平的影响:一项横断面研究。

Influence of Skin Phototype on the Level of Pain Perceived by Patients Receiving Enoxaparin: A Cross-Sectional Study.

作者信息

Díaz-González Candelaria de la Merced, Ramal-López Josefa María, González-Henríquez Juan José, de la Rosa-Hormiga Milagros

机构信息

Department of Nursing, Faculty of Health Sciences, University of Las Palmas de Gran Canaria, Juan de Quesada, 30, 35001 Las Palmas de Gran Canaria, Spain.

Department of Mathematics, Faculty of Health Sciences, University of Las Palmas de Gran Canaria, Juan de Quesada, 30, 35001 Las Palmas de Gran Canaria, Spain.

出版信息

Nurs Rep. 2022 Dec 2;12(4):958-967. doi: 10.3390/nursrep12040092.

DOI:10.3390/nursrep12040092
PMID:36548165
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9781531/
Abstract

Low Molecular Weight Heparin (LMWH) is commonly used as an antithrombotic in patients with reduced mobility. Its administration is performed by invasive technique (injections) that can cause pain: (1) Background: Pain and bruising are the most common side effects in patients treated with LMWH, but the skin phototype (PT) has never been included; (2) Methods: A cross-sectional descriptive study, developed in the Hospital Unit of Orthopedic and Trauma Surgery over one year. To classify all participants in the sample considering their skin PT and the different pain levels "during" and "after" the administration of enoxaparin. The STROBE checklist was used to evaluate the study. Data analyses were carried out: descriptive statistical analysis and analysis of Variance ANOVA of a non-parametric factor; (3) Results: The sample was 202 participants. The most frequent skin PTs were PT II 43.6% and PT III 33.2%. Mean pain after injection (1.96) was greater than pain during injection (1.4). Better natural protection against sunlight (high PT) would indicate greater post-injection pain; (4) Conclusions: Participants with a medium-high phototype (≥III) perceive a greater pain sensation than participants with a low phototype (≤II) after the administration of enoxaparin.

摘要

低分子量肝素(LMWH)常用于行动不便的患者以预防血栓形成。其给药通过侵入性技术(注射)进行,可能会引起疼痛:(1)背景:疼痛和瘀伤是接受LMWH治疗患者最常见的副作用,但皮肤光类型(PT)从未被纳入研究;(2)方法:一项横断面描述性研究,在骨科和创伤外科医院病房开展,为期一年。根据所有参与者的皮肤PT以及依诺肝素给药“期间”和“之后”的不同疼痛程度对样本中的所有参与者进行分类。采用STROBE清单对研究进行评估。进行数据分析:描述性统计分析和非参数因素的方差分析(ANOVA);(3)结果:样本为202名参与者。最常见的皮肤PT是PT II(43.6%)和PT III(33.2%)。注射后的平均疼痛程度(1.96)大于注射期间的疼痛程度(1.4)。对阳光的天然防护更好(高PT)表明注射后疼痛更剧烈;(4)结论:中高光类型(≥III)的参与者在接受依诺肝素给药后比低光类型(≤II)的参与者感觉到更强烈的疼痛感。