Kösling Christine, Schäfer Lisa, Hübner Claudia, Sebert Caroline, Hilbert Anja, Schmidt Ricarda
Integrated Research and Treatment Center Adiposity Diseases, Behavioral Medicine Research Unit, Department of Psychosomatic Medicine and Psychotherapy, Leipzig University Medical Center, 04103 Leipzig, Germany.
Brain Sci. 2022 Dec 2;12(12):1653. doi: 10.3390/brainsci12121653.
Although increased food cue reactivity is evidenced to be crucial to the development and maintenance of pediatric obesity, virtually nothing is known about the underlying neurophysiological aspects of food cue reactivity in children with obesity. Therefore, this study aimed at investigating neural characteristics in children with overweight or obesity using electroencephalography (EEG).
Electrophysiological brain activity was measured using EEG frequency band analysis in = 9 children with overweight or obesity versus = 16 children with normal weight (8-13 years) during the presentation of high- and low-calorie food pictures and images of appealing non-food stimuli.
Children with overweight or obesity showed significantly increased relative central beta band activity induced by high-calorie foods and appealing non-food stimuli compared to children with normal weight. Beyond significant effects of the scalp region on EEG activity, non-significant effects of stimulus category or weight status were seen for theta and alpha frequency bands.
This study demonstrated elevated beta band activity in children with overweight or obesity when viewing high-calorie food stimuli. Beta band activity may, thus, be a valuable target for neuromodulatory interventions in children with overweight or obesity.
尽管食物线索反应性增强被证明对儿童肥胖的发生和维持至关重要，但对于肥胖儿童食物线索反应性的潜在神经生理学方面几乎一无所知。因此，本研究旨在使用脑电图（EEG）研究超重或肥胖儿童的神经特征。
在呈现高热量和低热量食物图片以及有吸引力的非食物刺激图像期间，使用EEG频段分析测量了9名超重或肥胖儿童和16名正常体重儿童（8 - 13岁）的脑电生理活动。
与正常体重儿童相比，超重或肥胖儿童在看到高热量食物和有吸引力的非食物刺激时，相对中央β频段活动显著增加。除了头皮区域对EEG活动有显著影响外，对于θ和α频段，刺激类别或体重状态没有显著影响。
本研究表明，超重或肥胖儿童在观看高热量食物刺激时β频段活动升高。因此，β频段活动可能是超重或肥胖儿童神经调节干预的一个有价值的靶点。
