Department of Nutrition and Epidemiology, Medical University of Lodz, Zeligowskiego Street 7/9, 90-752 Lodz, Poland.
Department of Endocrine Disorders and Bone Metabolism, Medical University of Lodz, 90-752 Lodz, Poland.
Int J Environ Res Public Health. 2022 Dec 18;19(24):17023. doi: 10.3390/ijerph192417023.
Data obtained in recent years clearly demonstrate the aging process of European populations. Consequently, the incidence of osteoporosis has been rising. The aim of this study is to assess the quality of life (QoL) of women with osteoporosis. A total of 260 women participated in this study. The patient group consisted of 170 women with osteoporotic disorders. The control group consisted of 90 healthy women. Participants' quality of life was measured with the Qualeffo-41 Questionnaire. The total 25(OH)D concentration level was assessed with an assay using the chemiluminescent immunoassay. To assess the pain level, the Visual Analogue Scale (VAS) was used. To assess dietary behaviors, data were obtained by a 13-item Food Frequency Questionnaire. To assess the nutrition knowledge of participants, the Beliefs and Eating Habits Questionnaire was used. Based on the frequency of food intake, participants were classified into three patterns of behavior, i.e., Prudent, Western, and Not Prudent-Not Western. The patients assessed their quality of life as average (36.6 ± 19.9 points). The most favorable scores were obtained in the domains of "Ability to do jobs around the house" and "Mobility". The worst rated domain among the respondents was "Mental function". There were significant differences identified in quality of life depending on diet, nutritional knowledge, comorbidities and occurrence of fractures in the subjects. The individuals in the "Prudent" group reported a significantly higher quality of life as compared to the "Not Prudent-Not Western" and "Western" groups and those with high nutritional knowledge as compared to those with moderate and low. Lower quality of life was also observed among women with comorbidities and with bone fractures. Depending on serum 25(OH)D levels, poorer quality of life was characterized women with vitamin D deficiency. Patient education, implementation of effective methods aimed at alleviating pain and maintaining the optimal concentration of vitamin D can help improve the quality of life in patients with osteoporotic disorders.
近年来获得的数据清楚地表明了欧洲人口的老龄化过程。因此,骨质疏松症的发病率一直在上升。本研究旨在评估骨质疏松症女性的生活质量(QoL)。共有 260 名女性参与了这项研究。患者组由 170 名患有骨质疏松症的女性组成。对照组由 90 名健康女性组成。使用 Qualeffo-41 问卷评估参与者的生活质量。使用化学发光免疫测定法评估总 25(OH)D 浓度水平。使用视觉模拟量表(VAS)评估疼痛程度。使用 13 项食物频率问卷评估饮食行为。使用信念和饮食习惯问卷评估参与者的营养知识。根据食物摄入频率,参与者被分为三种行为模式,即谨慎、西方和不谨慎-不西方。患者将自己的生活质量评估为平均(36.6±19.9 分)。在“做家务的能力”和“行动能力”两个领域得分最高。受访者中评分最差的领域是“精神功能”。根据饮食、营养知识、合并症和骨折发生情况,生活质量存在显著差异。与“不谨慎-不西方”和“西方”组相比,“谨慎”组的个体报告的生活质量显著更高,与营养知识较高的个体相比,营养知识中等和较低的个体报告的生活质量更高。合并症和骨折的女性生活质量也较低。根据血清 25(OH)D 水平,维生素 D 缺乏的女性生活质量较差。对患者进行教育,实施有效缓解疼痛和维持最佳维生素 D 浓度的方法,可以帮助改善骨质疏松症患者的生活质量。