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幽门螺杆菌:临床实践中当前治疗选择的综述

Helicobacter Pylori: A Review of Current Treatment Options in Clinical Practice.

作者信息

Roberts Logan T, Issa Peter P, Sinnathamby Evan S, Granier Mallory, Mayeux Holly, Eubanks Treniece N, Malone Kevin, Ahmadzadeh Shahab, Cornett Elyse M, Shekoohi Sahar, Kaye Alan D

机构信息

LSUHSC-New Orleans School of Medicine, 1901 Perdido Street, New Orleans, LA 70112, USA.

Department of Anesthesiology, LSU Health Shreveport, 1501 Kings Highway, Shreveport, LA 71103, USA.

出版信息

Life (Basel). 2022 Dec 6;12(12):2038. doi: 10.3390/life12122038.

Abstract

BACKGROUND

When prescribing antibiotics, infection eradication rates, local resistance rates, and cost should be among the most essential considerations. is among the most common infections worldwide, and it can lead to burdensome sequela for the patient and the healthcare system, without appropriate treatment. Due to constantly fluctuating resistance rates, regimens must be constantly assessed to ensure effectiveness.

METHODS

This was a narrative review. The sources for this review are as follows: searching on PubMed, Google Scholar, Medline, and ScienceDirect; using keywords: , Treatment Options, Clinical Practice.

RESULTS

Multiple antibiotics are prescribed as part of the regimen to thwart high resistance rates. This can lead to unwanted adverse reactions and adherence issues, due to the amount and timing of medication administration, which also may contribute to resistance. Single-capsule combination capsules have reached the market to ease this concern, but brand-only may be problematic for patient affordability. Due to the previously mentioned factors, effectiveness and affordability must be equally considered.

CONCLUSIONS

This review will utilize guidelines to discuss current treatment options and give cost considerations to elicit the most effective regimen for the patient.

摘要

背景

在开具抗生素处方时,感染根除率、局部耐药率和成本应是最重要的考虑因素。在全球范围内是最常见的感染之一,如果没有适当的治疗,它会给患者和医疗系统带来沉重的后遗症负担。由于耐药率不断波动,必须不断评估治疗方案以确保有效性。

方法

这是一篇叙述性综述。本综述的资料来源如下:在PubMed、谷歌学术、Medline和科学Direct上进行搜索;使用关键词:治疗选择、临床实践。

结果

多种抗生素作为治疗方案的一部分被开具,以应对高耐药率。由于药物给药的数量和时间,这可能导致不良的不良反应和依从性问题,这也可能导致耐药性。单胶囊组合胶囊已投放市场以缓解这一担忧,但仅品牌药可能对患者的可承受性存在问题。由于上述因素,有效性和可承受性必须同等考虑。

结论

本综述将利用指南讨论当前的治疗选择,并给出成本考量,以确定对患者最有效的治疗方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0066/9785457/add9d51aa129/life-12-02038-g001.jpg

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