Toushik Sazzad Hossen, Roy Anamika, Alam Mohaimanul, Rahman Umma Habiba, Nath Nikash Kanti, Nahar Shamsun, Matubber Bidyut, Uddin Md Jamal, Roy Pantu Kumar
Institute for Smart Farm, Department of Food Hygiene and Safety, Gyeongsang National University, Jinju 52828, Republic of Korea.
ABEx Bio-Research Center, Azampur, Dakkhinkhan, Dhaka 1230, Bangladesh.
Microorganisms. 2022 Nov 28;10(12):2348. doi: 10.3390/microorganisms10122348.
Biofilm is a complex matrix made up of extracellular polysaccharides, DNA, and proteins that protect bacteria against physical, chemical, and biological stresses and allow them to survive in harsh environments. Safe and healthy foods are mandatory for saving lives. However, foods can be contaminated by pathogenic microorganisms at any stage from farm to fork. The contaminated foods allow pathogenic microorganisms to form biofilms and convert the foods into stigmatized poison for consumers. Biofilm formation by pathogenic microorganisms in agri-farm industries is still poorly understood and intricate to control. In biofilms, pathogenic bacteria are dwelling in a complex manner and share their genetic and physicochemical properties making them resistant to common antimicrobial agents. Therefore, finding the appropriate antibiofilm approaches is necessary to inhibit and eradicate the mature biofilms from foods and food processing surfaces. Advanced studies have already established several emerging antibiofilm approaches including plant- and microbe-derived biological agents, and they proved their efficacy against a broad-spectrum of foodborne pathogens. This review investigates the pathogenic biofilm-associated problems in agri-farm industries, potential remedies, and finding the solution to overcome the current challenges of antibiofilm approaches.
生物膜是一种由细胞外多糖、DNA和蛋白质组成的复杂基质，可保护细菌免受物理、化学和生物胁迫，并使其能够在恶劣环境中生存。安全健康的食品是拯救生命所必需的。然而，食品在从农场到餐桌的任何阶段都可能被致病微生物污染。被污染的食品会使致病微生物形成生物膜，并将食品转化为令消费者厌恶的毒物。农业农场行业中致病微生物形成生物膜的情况仍未得到充分了解，且难以控制。在生物膜中，致病细菌以复杂的方式存在，并共享它们的遗传和物理化学特性，从而使其对常见的抗菌剂具有抗性。因此，找到合适的抗生物膜方法对于抑制和根除食品及食品加工表面的成熟生物膜是必要的。先进的研究已经确立了几种新兴的抗生物膜方法，包括植物和微生物衍生的生物制剂，并且它们已证明对多种食源性病原体有效。本综述调查了农业农场行业中与致病生物膜相关的问题、潜在的补救措施，并寻找解决当前抗生物膜方法挑战的方案。
