Zitouni-Nourine Saida Hanane, Belyagoubi-Benhammou Nabila, El-Houaria Zitouni-Haouar Fatima, Douahi Omar, Chenafi Faouzia, Fetati Habiba, Chabane Sari Siham, Benmahieddine Assia, Zaoui Chahinez, Mekaouche Fatima Zohra Nadjet, Atik Bekkara Fawzia, Kambouche Nadia, Gismondi Angelo, Toumi Houari
Pharmaceutical Development Research Laboratory, Department of Pharmacy, Faculty of Medicine, Oran 1 Ahmed Ben Bella University, Oran 31000, Algeria.
Natural Products Laboratory, Department of Biology, Faculty of Natural and Life Sciences, Earth and Universe, University Abou-Bekr Belkaïd, Tlemcen 13000, Algeria.
Plants (Basel). 2022 Dec 9;11(24):3440. doi: 10.3390/plants11243440.
Turra subsp. (Asteraceae) is a medicinal plant in western Algeria. Traditionally, roots and inflorescences are employed as hypertensive agents and in the treatment of hemorrhoids. The current study evaluates the chemical composition, antioxidant, antimicrobial, and wound-healing properties of the root methanolic extract from subsp. . The content of total phenolics, flavonoids, and tannins was determined. In addition, the phenolic profile was typified. The studied plant extract resulted in being primarily composed of Apigenin, Kaempferol, and their derivatives. The total phenolic content was equal to 95.31 ± 2.90 mg GAE/g DW, while the number of flavonoids and condensed tannins was 16.01 ± 0.16 mg CE/g DW and 8.30 ± 0.65 mg CE/g DW, respectively. The methanolic extract was found to exhibit antioxidant activity towards the DPPH radical, with an IC of 7.99 ± 0.28 mg/mL and a TAC of 30.30 ± 0.54 mg AAE/g DW, as well as an antibacterial effect, especially against . No significant wound-healing property was observed, even though the histopathological observations showed enhanced wound-healing quality. According to our evidence, could represent a source of phytochemicals with potential beneficial effects for human health in terms of antioxidant and antibiotic properties, although further investigations on this species are needed.
Turra亚种（菊科）是阿尔及利亚西部的一种药用植物。传统上，其根和花序被用作降压剂和治疗痔疮。本研究评估了Turra亚种根甲醇提取物的化学成分、抗氧化、抗菌和伤口愈合特性。测定了总酚、黄酮和单宁的含量。此外，还对酚类成分进行了表征。所研究的植物提取物主要由芹菜素、山奈酚及其衍生物组成。总酚含量为95.31±2.90毫克没食子酸当量/克干重，黄酮和缩合单宁的含量分别为16.01±0.16毫克儿茶素当量/克干重和8.30±0.65毫克儿茶素当量/克干重。发现甲醇提取物对DPPH自由基具有抗氧化活性，IC50为7.99±0.28毫克/毫升，总抗氧化能力为30.30±0.54毫克抗坏血酸当量/克干重，并且具有抗菌作用，尤其是对[具体菌种未给出]。尽管组织病理学观察显示伤口愈合质量有所提高，但未观察到明显的伤口愈合特性。根据我们的证据，Turra亚种可能是一种植物化学物质的来源，在抗氧化和抗生素特性方面对人类健康具有潜在的有益影响，不过还需要对该物种进行进一步研究。
