Majumder Rajib, Ghosh Sanmitra, Das Arpita, Singh Manoj Kumar, Samanta Saikat, Saha Abinit, Saha Rudra P
Department of Biotechnology, School of Life Science & Biotechnology, Adamas University, Kolkata, 700126, India.
Department of Biological Sciences, School of Life Science & Biotechnology, Adamas University, Kolkata, 700126, India.
Curr Res Pharmacol Drug Discov. 2022 Oct 17;3:100136. doi: 10.1016/j.crphar.2022.100136. eCollection 2022.
ncRNA plays a very pivotal role in various biological activities ranging from gene regulation to controlling important developmental networks. It is imperative to note that this small molecule is not only present in all three domains of cellular life, but is an important modulator of gene regulation too in all these domains. In this review, we discussed various aspects of ncRNA biology, especially their role in bacteria. The last two decades of scientific research have proved that this molecule plays an important role in the modulation of various regulatory pathways in bacteria including the adaptive immune system and gene regulation. It is also very surprising to note that this small molecule is also employed in various processes related to the pathogenicity of virulent microorganisms.
非编码RNA在从基因调控到控制重要发育网络的各种生物活动中起着非常关键的作用。必须指出的是，这种小分子不仅存在于细胞生命的所有三个域中，而且在所有这些域中也是基因调控的重要调节因子。在这篇综述中，我们讨论了非编码RNA生物学的各个方面，特别是它们在细菌中的作用。过去二十年的科学研究证明，这种分子在调节细菌的各种调控途径中起着重要作用，包括适应性免疫系统和基因调控。同样令人惊讶的是，这种小分子也被用于与致病微生物致病性相关的各种过程中。
