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婚姻转变与老年人认知功能:韩国老龄化纵向研究(2006-2020 年)。

Marital transition and cognitive function among older adults: the korean Longitudinal Study of Aging (2006-2020).

机构信息

Department of Public Health, Graduate School, Yonsei University, Seoul, Republic of Korea.

Institute of Health Services Research, Yonsei University, Seoul, Republic of Korea.

出版信息

BMC Geriatr. 2022 Dec 28;22(1):1003. doi: 10.1186/s12877-022-03697-x.

Abstract

BACKGROUND

Marital status has been suggested as an associated factor for cognitive impairment. The consequences of marital transitions are still understudied. This study evaluated the influence of marital transitions on cognitive function using longitudinal, nationwide data of Korean older adults.

METHODS

This research comprised a longitudinal sample of older adults aged ≥ 45 years old, drawn from the Korean Longitudinal Study of Aging (2006-2020). Marital transition was determined through the biennial assessment of change in marital status; cognitive function was measured using the Korean version of the Mini-Mental State Examination. We employed general estimating equations to assess the temporal effect of marital transition on cognitive function.

RESULTS

Compared to married individuals, the odds ratios (ORs) of cognitive decline were higher in not married and transitioned out of marriage participants: men (OR 1.32, 95% confidence interval (CI) 0.96-1.82; OR 1.42, 95% CI 0.90-2.24), women (OR 1.21, 95% CI 1.03-1.42; OR 1.20, 95% CI 1.01-1.52), respectively, despite the findings being not statistically significant in men. The participants who transitioned out of marriage over time also showed greater ORs for mild cognitive impairment: men (OR 1.39, 95% CI 0.79-1.87), women (OR 1.33, 95% CI 1.05-1.80), and dementia: men (OR 1.60, 95% CI 0.85-1.99), women: (OR 1.49, 95% CI 1.20-2.19).

CONCLUSION

Marital transition is found to be associated with cognitive function decline. Not-married individuals and those who became divorced or widowed were associated with the risk of cognitive function decline. Particular attention should be paid to these marital transitioned groups.

摘要

背景

婚姻状况被认为是认知障碍的相关因素。婚姻转变的后果仍在研究之中。本研究使用韩国老年人的纵向全国性数据评估了婚姻转变对认知功能的影响。

方法

本研究包括了年龄在 45 岁及以上的老年人的纵向样本,这些人来自韩国老龄化纵向研究(2006-2020 年)。通过每两年评估一次婚姻状况的变化来确定婚姻转变;认知功能使用韩国版的简易精神状态检查进行测量。我们采用一般估计方程来评估婚姻转变对认知功能的时间效应。

结果

与已婚者相比,未婚和婚姻状态转变为离异或丧偶的参与者认知能力下降的几率更高:男性(比值比 1.32,95%置信区间 0.96-1.82;比值比 1.42,95%置信区间 0.90-2.24),女性(比值比 1.21,95%置信区间 1.03-1.42;比值比 1.20,95%置信区间 1.01-1.52),尽管男性的结果没有统计学意义。随着时间的推移,婚姻状态转变为离异或丧偶的参与者也表现出更高的轻度认知障碍的几率:男性(比值比 1.39,95%置信区间 0.79-1.87),女性(比值比 1.33,95%置信区间 1.05-1.80)和痴呆症:男性(比值比 1.60,95%置信区间 0.85-1.99),女性(比值比 1.49,95%置信区间 1.20-2.19)。

结论

婚姻转变与认知功能下降有关。未婚者和离异或丧偶者与认知功能下降的风险相关。应特别关注这些婚姻转变的群体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a6c2/9798712/f77f128cbc89/12877_2022_3697_Fig1_HTML.jpg

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