Ye Peitao, Li Qiasheng, Jian Wenhua, Liu Shuyi, Tan Lunfang, Chen Wenya, Zhang Dongying, Zheng Jinping
National Center for Respiratory Medicine, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Faculty of Medicine, Macau University of Science and Technology, Macau, China.
Front Physiol. 2022 Dec 12;13:1079468. doi: 10.3389/fphys.2022.1079468. eCollection 2022.
Electronic stethoscopes are widely used for cardiopulmonary auscultation; their audio recordings are used for the intelligent recognition of cardiopulmonary sounds. However, they generate noise similar to a crackle during use, significantly interfering with clinical diagnosis. This paper will discuss the causes, characteristics, and occurrence rules of the fake crackle and establish a reference for improving the reliability of the electronic stethoscope in lung auscultation. A total of 56 participants with healthy lungs (no underlying pulmonary disease, no recent respiratory symptoms, and no adventitious lung sound, as confirmed by an acoustic stethoscope) were enrolled in this study. A 30-s audio recording was recorded from each of the nine locations of the larynx and lungs of each participant with a 3M Littmann 3200 electronic stethoscope, and the audio was output in diaphragm mode and auscultated by the clinician. The doctor identified the fake crackles and analyzed their frequency spectrum. High-pass and low-pass filters were used to detect the frequency distribution of the fake crackles. Finally, the fake crackle was artificially regenerated to explore its causes. A total of 500 audio recordings were included in the study, with 61 fake crackle audio recordings. Fake crackles were found predominantly in the lower lung. There were significant differences between lower lung and larynx ( < 0.001), lower lung and upper lung ( = 0.005), lower lung and middle lung ( = 0.005), and lower lung and infrascapular region ( = 0.027). Furthermore, more than 90% of fake crackles appeared in the inspiratory phase, similar to fine crackles, significantly interfering with clinical diagnosis. The spectral analysis revealed that the frequency range of fake crackles was approximately 250-1950 Hz. The fake crackle was generated when the diaphragm of the electronic stethoscope left the skin slightly but not completely. Fake crackles are most likely to be heard when using an electronic stethoscope to auscultate bilateral lower lungs, and the frequency of a fake crackle is close to that of a crackle, likely affecting the clinician's diagnosis.
电子听诊器广泛应用于心肺听诊;其音频记录用于心肺音的智能识别。然而,它们在使用过程中会产生类似于爆裂音的噪声,严重干扰临床诊断。本文将探讨假爆裂音的产生原因、特征及出现规律,为提高电子听诊器肺部听诊的可靠性提供参考。本研究共纳入56名肺部健康的参与者(经声学听诊器确认无潜在肺部疾病、近期无呼吸道症状且无肺部附加音)。使用3M Littmann 3200电子听诊器从每位参与者的喉部和肺部的九个位置分别记录30秒的音频,音频以膜片模式输出并由临床医生听诊。医生识别出假爆裂音并分析其频谱。使用高通和低通滤波器检测假爆裂音的频率分布。最后,人工重现假爆裂音以探究其产生原因。本研究共纳入500份音频记录,其中有61份假爆裂音音频记录。假爆裂音主要出现在下肺部。下肺部与喉部(<0.001)、下肺部与上肺部(=0.005)、下肺部与中肺部(=0.005)以及下肺部与肩胛下区域(=0.027)之间存在显著差异。此外,超过90%的假爆裂音出现在吸气阶段,类似于细爆裂音,严重干扰临床诊断。频谱分析显示,假爆裂音的频率范围约为250 - 1950赫兹。当电子听诊器的膜片稍微但未完全离开皮肤时会产生假爆裂音。使用电子听诊器听诊双侧下肺部时最容易听到假爆裂音,且假爆裂音的频率与爆裂音接近,可能会影响临床医生的诊断。