Ghazzawi Raghad A, Alqurashi Mohammed G, Almalki Nada A, Alosaimi Ashwaq K, Al Hawsawi Khalid
Medicine and Surgery, King Faisal Specialist Hospital and Research Centre, Jeddah, SAU.
Internal Medicine, King Saud Bin Abdulaziz University for Health Sciences College of Medicine, Jeddah, SAU.
Cureus. 2022 Nov 23;14(11):e31846. doi: 10.7759/cureus.31846. eCollection 2022 Nov.
Halogenoderma (HD) is an uncommon dermatosis that develops following exposure to halogens such as iodide and bromide, referred to as iododerma and bromoderma, respectively. Here, we report the case of a 40-year-old male who presented with a three-week history of slightly itchy progressive skin lesions associated with low-grade fever and malaise. The patient had a history of using food supplements containing iodide and bromide for four months prior to the appearance of skin rashes. Skin examination revealed multiple crusted papules and nodules scattered on his face, neck, and trunk. A skin biopsy was taken from the lesions. The epidermis showed crustation, exocytosis of neutrophils, and multiple intraepidermal abscesses. The dermis showed heavy cellular infiltrates composed mainly of neutrophils. The skin lesions disappeared completely after the cessation of food supplements, along with the use of topical corticosteroids for a few weeks.
卤化皮肤病（HD）是一种罕见的皮肤病，在接触碘化物和溴化物等卤素后发生，分别称为碘疹和溴疹。在此，我们报告一例40岁男性病例，该患者有为期三周的轻度瘙痒性进行性皮肤损害病史，伴有低热和不适。患者在皮疹出现前四个月有服用含碘化物和溴化物的食品补充剂的历史。皮肤检查发现其面部、颈部和躯干散在多个结痂丘疹和结节。从病变处取了皮肤活检。表皮显示结痂、中性粒细胞外渗和多个表皮内脓肿。真皮显示主要由中性粒细胞组成的大量细胞浸润。停用食品补充剂并局部使用皮质类固醇几周后，皮肤损害完全消失。
