Greenspan Sasha E, Peloso Pedro, Fuentes-González Jesualdo A, Bletz Molly, Lyra Mariana L, Machado Ibere F, Martins Renato A, Medina Daniel, Moura-Campos Diego, Neely Wesley J, Preuss Jackson, Sturaro Marcelo J, Vaz Renata I, Navas Carlos A, Toledo Luís Felipe, Tozetti Alexandro M, Vences Miguel, Woodhams Douglas C, Haddad Célio F B, Pienaar Jason, Becker C Guilherme
Department of Biological Sciences, The University of Alabama, Tuscaloosa, AL, 35487, USA.
Programa de Pós Gradução em Zoologia, Universidade Federal do Pará/Museu Paraense Emílio Goeldi, Belém, Pará, 66077-530, Brazil.
Anim Microbiome. 2022 Dec 29;4(1):69. doi: 10.1186/s42523-022-00220-w.
Microbial diversity positively influences community resilience of the host microbiome. However, extinction risk factors such as habitat specialization, narrow environmental tolerances, and exposure to anthropogenic disturbance may homogenize host-associated microbial communities critical for stress responses including disease defense. In a dataset containing 43 threatened and 90 non-threatened amphibian species across two biodiversity hotspots (Brazil's Atlantic Forest and Madagascar), we found that threatened host species carried lower skin bacterial diversity, after accounting for key environmental and host factors. The consistency of our findings across continents suggests the broad scale at which low bacteriome diversity may compromise pathogen defenses in species already burdened with the threat of extinction.
微生物多样性对宿主微生物组的群落恢复力具有积极影响。然而，诸如栖息地特化、狭窄的环境耐受性以及暴露于人为干扰等灭绝风险因素，可能会使对包括疾病防御在内的应激反应至关重要的宿主相关微生物群落趋于同质化。在一个包含两个生物多样性热点地区（巴西大西洋森林和马达加斯加）的43种受威胁两栖动物和90种非受威胁两栖动物的数据集里，我们发现，在考虑了关键环境和宿主因素后，受威胁宿主物种的皮肤细菌多样性较低。我们在各大洲的研究结果具有一致性，这表明低细菌群落多样性可能在广泛范围内损害那些已经面临灭绝威胁物种的病原体防御能力。
