Zhu Wei, Chang Liming, Zhang Meihua, Chen Qiheng, Sui Lulu, Shen Cheng, Jiang Jianping
CAS Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization & Ecological Restoration Biodiversity Conservation Key Laboratory of Sichuan Province, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
University of Chinese Academy of Sciences, Beijing 100049, China.
iScience. 2024 May 3;27(6):109907. doi: 10.1016/j.isci.2024.109907. eCollection 2024 Jun 21.
Comprehending the determinants of host-associated microbiota is pivotal in microbial ecology. Yet, the links between climatic factors and variations in host-associated microbiota necessitate further clarification. Mountain-dwelling amphibians, with limited dispersal abilities, serve as valuable models for addressing these questions. Our study, using 126 amphibian-associated microbial samples (64 gut and 62 skin) and 101 environmental microbial samples (51 soil and 50 water) from the eastern Tibetan Plateau, revealed host factors as primary drivers of the variations in host-associated microbiota. However, climatic factors contributed to additional variations in gut microbial beta-diversity and skin microbial function. Water microbiota were identified as a significant contributor to the amphibian-associated microbiomes, with their climate-driven variations mediating an indirect association between the variations in climatic factors and host-associated microbiota. These findings extend our understanding of the assembly of host-associated microbiota in amphibians, emphasizing the significance of microbiota in evaluating the impact of climate change on animals.
了解宿主相关微生物群的决定因素在微生物生态学中至关重要。然而，气候因素与宿主相关微生物群变化之间的联系仍需进一步阐明。由于扩散能力有限，栖息在山区的两栖动物成为解决这些问题的宝贵模型。我们的研究使用了来自青藏高原东部的126个两栖动物相关微生物样本（64个肠道样本和62个皮肤样本）和101个环境微生物样本（51个土壤样本和50个水样），结果表明宿主因素是宿主相关微生物群变化的主要驱动因素。然而，气候因素导致了肠道微生物β多样性和皮肤微生物功能的额外变化。水微生物群被确定为两栖动物相关微生物组的重要贡献者，其受气候驱动的变化介导了气候因素变化与宿主相关微生物群变化之间的间接关联。这些发现扩展了我们对两栖动物宿主相关微生物群组装的理解，强调了微生物群在评估气候变化对动物影响方面的重要性。
