Röth E, Szmolenszky T, Török B
Int Urol Nephrol. 1978;10(4):335-47. doi: 10.1007/BF02082373.
The function of canine kidneys stored with hypothermic solutions (Rheomacrodex, Collins4, Sacks) was studied in acute autologous reperfusion models. Changes in the perfusates (increase in LDH level and minor increase in K+ level), as well as the quantitative and qualitative properties (proteinuria) of the urine produced by the graft may be ascribed to storage and revascularization which affect the cells and their membranes. The alterations of the circulatory parameters demonstrable at the outset and during revascularization are due to an increase in renovascular resistance of hypothermic origin on the one hand, and to acute tubular epithelial damage inherent in the procedure, on the other.
在急性自体再灌注模型中研究了用低温溶液（低分子右旋糖酐、柯林斯4号溶液、萨克斯溶液）保存的犬肾的功能。灌注液的变化（乳酸脱氢酶水平升高和钾离子水平轻微升高）以及移植肾产生的尿液的定量和定性特性（蛋白尿）可能归因于影响细胞及其膜的保存和血管重建。在开始时和血管重建期间可证实的循环参数改变一方面是由于低温源性肾血管阻力增加，另一方面是由于该过程中固有的急性肾小管上皮损伤。
