Jain Tarang Kumar, Jha Rahul, Tiwari Anushree, Agrawal Neha, Mali Sheetal, Sinha Anamika, Bagde Hiroj, Singh Ramanpal
Department of Oral and Maxillofacial Surgery, Rungta College of Dental Sciences & Research, Bhilai, IND.
Department of Periodontology, Rungta College of Dental Sciences & Research, Bhilai, IND.
Cureus. 2022 Nov 24;14(11):e31855. doi: 10.7759/cureus.31855. eCollection 2022 Nov.
The study aimed to compare the clinical efficacy, safety, and acceptability of buffered lidocaine (8.4% sodium bicarbonate and 2% lidocaine with 1:80,000 adrenaline) versus non-buffered lidocaine (2% lidocaine with 1:80,000 adrenaline) during inferior alveolar nerve block.
Fifty patients who required bilateral extractions in a single arch were included in this study. One hundred extractions were carried out, and all of the patients had nerve blocks during the procedure. We also took note of the patient's pain level as measured on a visual analog scale, as well as the start of the action, duration of postoperative analgesia, and occurrence of any problems. The duration of anesthesia was assessed by the feeling of numbness and the first sign of pain.
All the patients in both study groups reported subjective numbness of the lips and tongue. The depth of anesthesia was evaluated by pain and comfort during the procedure with a visual analog scale and showed no significant difference between the two groups. The onset of action for the pterygomandibular nerve block was 1.240.31 minutes (buffered) and 1.710.51 minutes (non-buffered). When compared, the duration of anesthesia was 327.18102.98 minutes (buffered) and 129.0826.85 minutes (non-buffered).
This study concludes that the buffered solution has a faster onset of action than the non-buffered solution. Both solutions exhibit similar intraoperative efficacy. The duration of postoperative anesthesia was prolonged with buffering. Buffering also reduced pain scores during the early postoperative period.
本研究旨在比较在下牙槽神经阻滞过程中,缓冲利多卡因(8.4%碳酸氢钠和2%利多卡因加1:80,000肾上腺素)与非缓冲利多卡因(2%利多卡因加1:80,000肾上腺素)的临床疗效、安全性和可接受性。
本研究纳入了50例需要在单颌进行双侧拔牙的患者。共进行了100次拔牙,所有患者在手术过程中均接受了神经阻滞。我们还记录了患者在视觉模拟量表上测量的疼痛程度,以及起效时间、术后镇痛持续时间和任何问题的发生情况。麻醉持续时间通过麻木感和疼痛的第一个迹象来评估。
两个研究组的所有患者均报告嘴唇和舌头有主观麻木感。通过手术过程中的疼痛和舒适度使用视觉模拟量表评估麻醉深度,两组之间无显著差异。翼下颌神经阻滞的起效时间为1.24±0.31分钟(缓冲组)和1.71±0.51分钟(非缓冲组)。相比之下,麻醉持续时间为327.18±102.98分钟(缓冲组)和129.08±26.85分钟(非缓冲组)。
本研究得出结论,缓冲溶液的起效时间比非缓冲溶液更快。两种溶液在术中表现出相似的疗效。缓冲延长了术后麻醉的持续时间。缓冲还降低了术后早期的疼痛评分。