Fujian Medical University Union Hospital, Fuzhou City, Fujian Province, China.
Clin Transplant. 2023 Feb;37(2):e14902. doi: 10.1111/ctr.14902. Epub 2023 Jan 11.
The Organ Procurement Organization (OPO) was established in August 2018. The organization's workload, work efficiency, and quality control of organ donation and procurement have continuously improved, making it one of the most successful OPOs in Fujian Province. This study explores the factors that influence the success and failure of organ donation in Fujian Province, China.
Data from 236 potential organ donors registered at an OPO in Fujian Province between January 2020 and May 2022 were retrospectively analyzed.
Among the 236 potential organ donors, 71 cases of organ donation were successful (30.08% conversion rate). Univariate analysis showed that demographic factors, such as differences in sex, age, marital status, and domicile location, were significantly associated with successful organ donation (p < .05). Among hospital-related factors, differences in hospital departments were significant (p < .05). Considering disease-related factors, spontaneous respiration was significant (p < .05). For factors related to organ donation, differences in coordinators were significant (p < .05). Multivariate analysis showed that age, domicile location, spontaneous respiration, and coordinators influenced organ donation success (p < .05). Multifactor analysis revealed that factors, such as age ≤50 years, domicile location in other provinces, no spontaneous respiration, and highly skilled coordinators, could promote successful organ donation.
Programs should clarify the screening criteria for key potential organ donors, enhance the promotion and popularization of organ donation, and boost the number and professional skills of organ donation coordinators to improve the organ donation conversion rate.
器官获取组织（OPO）于 2018 年 8 月成立。该组织的工作量、工作效率和器官捐献获取的质量控制不断提高，使其成为福建省最成功的 OPO 之一。本研究探讨了影响中国福建省器官捐献成功与失败的因素。
回顾性分析了 2020 年 1 月至 2022 年 5 月期间在福建省一家 OPO 登记的 236 名潜在器官捐献者的数据。
在 236 名潜在器官捐献者中，71 例器官捐献成功（转化率为 30.08%）。单因素分析表明，性别、年龄、婚姻状况和籍贯等人口统计学因素与器官捐献成功显著相关（p<0.05）。在与医院相关的因素中，科室差异显著（p<0.05）。考虑与疾病相关的因素，自主呼吸有显著差异（p<0.05）。对于与器官捐献相关的因素，协调员之间存在显著差异（p<0.05）。多因素分析表明，年龄、籍贯、自主呼吸和协调员影响器官捐献的成功率（p<0.05）。多因素分析显示，年龄≤50 岁、籍贯在其他省份、无自主呼吸和技能熟练的协调员等因素可以促进器官捐献的成功。
应明确关键潜在器官捐献者的筛选标准，加强器官捐献的宣传和推广，提高器官捐献协调员的数量和专业技能，以提高器官捐献转化率。
