Suppr超能文献

肉芽肿性乳腺炎——病例报告

Granulomatous mastitis - Case report.

作者信息

Ribeiro Catarina Gil, Pimentel Alice, Lages Rita, Ferreira Ana Isabel, da Silva João Barros

机构信息

Departamento de Cirurgia de ULS Tâmega e Sousa, Penafiel, Portugal.

Departamento de Cirurgia de ULS Tâmega e Sousa, Penafiel, Portugal.

出版信息

Int J Surg Case Rep. 2025 Apr;129:111222. doi: 10.1016/j.ijscr.2025.111222. Epub 2025 Mar 27.

Abstract

INTRODUCTION AND IMPORTANCE

Idiopathic granulomatous mastitis (IGM) is a rare, benign, and chronic inflammatory breast disease with unclear etiology and no standardized treatment. It often presents as a painful breast mass that mimics breast cancer, necessitating thorough diagnostic evaluation.

CASE PRESENTATION

This report discusses a case of a 39-year-old pregnant woman with IGM associated with erythema nodosum, a poorly understood co-occurrence. Initial treatment included antibiotics and surgical drainage for an abscess. Despite multiple interventions, including corticosteroids and methotrexate, the disease persisted with recurrent episodes.

CLINICAL DISCUSSION

This case underscores the complexities of managing IGM, highlighting its association with systemic manifestations such as erythema nodosum. Current therapeutic approaches range from conservative management to immunosuppressive therapy and surgery, with outcomes varying widely.

CONCLUSION

Further studies are needed to elucidate the pathophysiology and establish optimal treatment strategies for IGM, particularly in the context of systemic involvement.

摘要

引言与重要性

特发性肉芽肿性乳腺炎(IGM)是一种罕见的、良性的慢性炎症性乳腺疾病,病因不明,且无标准化治疗方法。它常表现为疼痛性乳腺肿块,酷似乳腺癌,因此需要进行全面的诊断评估。

病例介绍

本报告讨论了一例39岁的孕妇,患有与结节性红斑相关的IGM,这种同时出现的情况了解甚少。初始治疗包括针对脓肿使用抗生素和手术引流。尽管进行了多种干预措施,包括使用皮质类固醇和甲氨蝶呤,但疾病仍持续发作。

临床讨论

该病例突显了管理IGM的复杂性,强调了其与结节性红斑等全身表现的关联。目前的治疗方法从保守管理到免疫抑制治疗和手术不等,结果差异很大。

结论

需要进一步研究以阐明IGM的病理生理学,并建立最佳治疗策略,特别是在存在全身受累的情况下。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0e8/11997340/3525b19312a1/gr1.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验