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婴儿肛瘘:哪些会复发?

Fistula in ano in infants: who recurs?

作者信息

Novotny Nathan M, Mann Monica J S, Rescorla Frederick J

机构信息

Department of Surgery, Indiana University School of Medicine, 545 Barnhill Dr. EH 202, Indianapolis, IN 46202, USA.

出版信息

Pediatr Surg Int. 2008 Nov;24(11):1197-9. doi: 10.1007/s00383-008-2236-3.

Abstract

INTRODUCTION

Fistula in ano is a common malady in infancy. However, relatively little literature is devoted to it. Our aim was to describe the natural history and identify predictors of which children will ultimately recur.

METHODS

A retrospective review of patients less than 3 years old undergoing anal fistulotomy was performed between May 2002 and November 2007 at a tertiary children's hospital. Demographics, preoperative, operative, and postoperative characteristics were collected in each group and evaluated by biostatistical analysis. P values <0.05 were considered significant.

RESULTS

A total of 92 children undergoing anal fistulotomy were identified. The median age was 6 months. Twelve children (13%) had recurrences and two of the 12 had multiple recurrences. Children who had recurrences were older (12.9 vs. 7.5 months, P < 0.05) and were more likely to have a previous abscess (20 vs. 6%, P < 0.05). In addition, children with recurrences had pus noted at the time of surgery more than children who did not recur (23 vs. 8%, respectively, P < 0.05). There were no major complications.

CONCLUSIONS

Fistula in ano in infants is a relatively benign process with most children having no serious sequelae. However, a not insignificant portion (13%) of children developed recurrences. Older children who developed fistulas were more likely to have a recurrence than younger, and children who had previous episodes of perianal abscess or pus noted at the time of surgery were more likely to recur.

摘要

引言

先天性肛瘘在婴儿期是一种常见疾病。然而,针对它的文献相对较少。我们的目的是描述其自然病史,并确定哪些儿童最终会复发的预测因素。

方法

对2002年5月至2007年11月在一家三级儿童医院接受肛瘘切开术的3岁以下患者进行回顾性研究。收集每组患者的人口统计学、术前、手术和术后特征,并通过生物统计学分析进行评估。P值<0.05被认为具有统计学意义。

结果

共确定92例接受肛瘘切开术的儿童。中位年龄为6个月。12名儿童(13%)复发,其中2名多次复发。复发的儿童年龄较大(12.9个月对7.5个月,P<0.05),且更有可能有既往脓肿病史(20%对6%,P<0.05)。此外,复发儿童在手术时发现有脓液的比例高于未复发儿童(分别为23%对8%,P<0.05)。无重大并发症。

结论

婴儿先天性肛瘘是一个相对良性的过程,大多数儿童没有严重后遗症。然而,有相当一部分儿童(13%)复发。发生肛瘘的大龄儿童比小龄儿童更易复发,既往有肛周脓肿发作或手术时发现有脓液的儿童更易复发。

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