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食用蕈菌萜类化合物的生物活性和生物合成研究进展。

Progress in biological activities and biosynthesis of edible fungi terpenoids.

机构信息

College of Food Science, South China Agricultural University, Guangzhou, China.

Guangdong Provincial Key Laboratory of Protein Function and Regulation in Agricultural Organisms, College of Life Sciences, South China Agricultural University, Guangzhou, China.

出版信息

Crit Rev Food Sci Nutr. 2023;63(25):7288-7310. doi: 10.1080/10408398.2022.2045559. Epub 2022 Mar 3.

DOI:10.1080/10408398.2022.2045559
PMID:35238261
Abstract

The edible fungi have both edible and medicinal functions, in which terpenoids are one of the most important active ingredients. Terpenoids possess a wide range of biological activities and show great potential in the pharmaceutical and healthcare industries. In this review, the diverse biological activities of edible fungi terpenoids were summarized with emphasis on the mechanism of anti-cancer and anti-inflammation. Subsequently, this review focuses on advances in knowledge and understanding of the biosynthesis of terpenoids in edible fungi, especially in the generation of sesquiterpenes, diterpenes, and triterpenes. This paper is aim to provide an overview of biological functions and biosynthesis developed for utilizing the terpenoids in edible fungi.

摘要

食用真菌兼具食用和药用功能,其中萜类化合物是最重要的活性成分之一。萜类化合物具有广泛的生物活性,在制药和保健行业具有巨大的潜力。在这篇综述中,总结了食用真菌萜类化合物的多种生物活性,重点介绍了其抗癌和抗炎作用的机制。随后,本文重点介绍了食用真菌萜类化合物生物合成方面的知识和认识进展,特别是在半萜烯、二萜和三萜的生成方面。本文旨在概述为利用食用真菌中的萜类化合物而开发的生物功能和生物合成。

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