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腹腔注射来自剥夺快速眼动睡眠(PS)大鼠的脑提取物后快速眼动睡眠(PS)增加。

Increase of paradoxical sleep (PS) by intraperitoneal injection of brain extract from PS-deprived rats.

作者信息

Wetzel W, Stark H, Matthies H

机构信息

Institute of Pharmacology and Toxicology, Medical Academy, GDR, Magdeburg.

出版信息

Pharmacol Biochem Behav. 1987 Jul;27(3):537-9. doi: 10.1016/0091-3057(87)90362-5.

DOI:10.1016/0091-3057(87)90362-5
PMID:3659077
Abstract

Intraperitoneal injection of a brain extract obtained from paradoxical sleep-(PS) deprived donor rats resulted in a small but significant increase of PS in normal recipient rats. Brain extract of non-deprived control rats was without effect. The results provide further evidence for the existence of a PS-inducing factor accumulating in the brain during PS deprivation.

摘要

向正常受体大鼠腹腔注射从剥夺异相睡眠(PS)的供体大鼠获得的脑提取物,导致正常受体大鼠的PS出现小幅但显著的增加。未剥夺睡眠的对照大鼠的脑提取物则没有效果。这些结果为PS剥夺期间在大脑中积累的PS诱导因子的存在提供了进一步的证据。

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