Department of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University, Aarhus University Hospital, Aarhus, Denmark.
National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.
BMJ. 2023 Jan 3;380:e072308. doi: 10.1136/bmj-2022-072308.
To examine labour market participation and retirement among patients with stroke and matched people in the general population according to stroke subtype.
Nationwide, population based, matched cohort study.
Danish Stroke Registry, covering all Danish hospitals, and other nationwide registries (2005-18).
Patients (aged 18-60 years and active in the labour market) with a first time diagnosis of ischaemic stroke (n=16 577), intracerebral haemorrhage (n=2025), or subarachnoid haemorrhage (n=4305), and individuals from the general population, matched on age, sex, and calendar year (n=134 428). The median Scandinavian stroke scale score was 55.
Unweighted prevalences of labour market participation, receipt of sick leave benefits, receipt of disability pension, voluntary early retirement, state pension, and death were computed for each week and up to five years after stroke diagnosis. A log-linear Poisson model was used to obtain exact prevalence estimates as well as propensity score weighted prevalence differences and prevalence ratios at six months, one year, two years, and five years after stroke diagnosis.
Most patients (62% of those with ischaemic stroke, 69% of those with intracerebral haemorrhage, and 52% of those with subarachnoid haemorrhage) went on sick leave within three weeks of diagnosis. Prevalence of labour market participation among patients with ischaemic stroke compared with matched individuals from the general population was 56.6% versus 96.6% at six months, and 63.9% versus 91.6% at two years. Prevalence of sick leave was 39.8% versus 2.6% at six months, and 15.8% versus 3.8% at two years. Prevalence of receipt of a disability pension was 0.9% versus 0.2% at six months, and 12.2% versus 0.6% at two years. Adjusting for socioeconomic and comorbidity differences between patients and matched individuals from the general population using propensity score weighting methods had little impact on contrasts. Patients with intracerebral haemorrhage had higher prevalences of sick leave and receipt of a disability pension and thus a lower prevalence of labour market participation, while prevalences for patients with subarachnoid haemorrhage were similar in magnitude to those for patients with ischaemic stroke.
In a highly resourced country, about two thirds of working age adults with ischaemic stroke of primarily mild severity participated in the labour market two years after diagnosis. Sick leave and receipt of a disability pension were the most common reasons for non-participation. Patients with intracerebral haemorrhage were less likely to return to the labour market than patients with ischaemic stroke and subarachnoid haemorrhage.
根据卒中亚型,研究卒中患者与普通人群中匹配个体的劳动力市场参与和退休情况。
全国范围内基于人群的匹配队列研究。
丹麦卒中登记处,覆盖所有丹麦医院和其他全国性登记处(2005-18 年)。
首次诊断为缺血性卒中(n=16577)、颅内出血(n=2025)或蛛网膜下腔出血(n=4305)的年龄在 18-60 岁且活跃于劳动力市场的患者,以及年龄、性别和日历年份相匹配的普通人群中的个体(n=134428)。斯堪的纳维亚卒中量表的中位数评分为 55。
计算了每个患者每周和卒中诊断后长达 5 年的劳动力市场参与率、休病假、领取残疾抚恤金、自愿提前退休、领取国家养老金和死亡的未加权患病率。使用对数线性泊松模型获得了精确的患病率估计值,以及卒中诊断后 6 个月、1 年、2 年和 5 年的倾向评分加权患病率差异和患病率比。
大多数患者(缺血性卒中患者的 62%、颅内出血患者的 69%和蛛网膜下腔出血患者的 52%)在诊断后 3 周内休病假。与普通人群中匹配个体相比,缺血性卒中患者的劳动力市场参与率为 6 个月时 56.6%,2 年时 63.9%;6 个月时休病假的患病率为 39.8%,2 年时为 15.8%;6 个月时领取残疾抚恤金的患病率为 0.9%,2 年时为 12.2%。使用倾向评分加权方法调整患者与普通人群中匹配个体之间的社会经济和合并症差异后,对对比的影响很小。颅内出血患者的病假和残疾抚恤金患病率较高,因此劳动力市场参与率较低,而蛛网膜下腔出血患者的患病率与缺血性卒中患者相似。
在资源丰富的国家,大约三分之二的主要为轻度严重程度的缺血性卒中的成年劳动力在卒中诊断后两年仍参与劳动力市场。病假和领取残疾抚恤金是最常见的不参与原因。与缺血性卒中和蛛网膜下腔出血患者相比,颅内出血患者重返劳动力市场的可能性较小。