Song In Gyu
Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.
Clin Exp Pediatr. 2023 Jul;66(7):281-287. doi: 10.3345/cep.2022.00822. Epub 2022 Dec 30.
During the last several decades, the number of preterm infants has increased, and their survival rate has improved owing to advances in perinatal care. As more preterm infants survive, many studies examine their neurodevelopmental outcomes. This study aimed to summarize the neurodevelopmental outcomes of preterm infants according to gestational age at birth using a recently published meta-analysis. The prevalence of neurodevelopmental impairment and behavioral disorders decreased as gestational age and birth weight increased. Recent studies reported that proactive neonatal treatment of periviable preterm infants (gestational age, 22-24 weeks) could improve their prognosis. Moderate and late preterm infants reportedly have less severe disease than very preterm infants; nonetheless, they still experience adverse neurodevelopmental outcomes compared to term infants. Neonatal morbidities such as bronchopulmonary dysplasia and retinopathy of prematurity are associated with poor neurodevelopmental outcomes. Despite improvements in neonatal care, prematurity is still associated with poor neurodevelopmental outcomes. To ensure timely intervention, the establishment of a follow-up system for premature infants is necessary.
在过去几十年中，早产儿数量有所增加，由于围产期护理的进步，他们的存活率也有所提高。随着越来越多的早产儿存活下来，许多研究开始关注他们的神经发育结局。本研究旨在通过一项最近发表的荟萃分析，总结不同出生孕周早产儿的神经发育结局。神经发育障碍和行为障碍的患病率随着孕周和出生体重的增加而降低。最近的研究报告称，对可存活早产儿（孕周22 - 24周）进行积极的新生儿治疗可以改善其预后。据报道，中度和晚期早产儿的病情不如极早产儿严重；尽管如此，与足月儿相比，他们仍然会出现不良的神经发育结局。支气管肺发育不良和早产儿视网膜病变等新生儿疾病与不良的神经发育结局相关。尽管新生儿护理有所改善，但早产仍然与不良的神经发育结局有关。为确保及时干预，有必要建立早产儿随访系统。
