Kimchy Alexandra V, Umoren Mfonsio D, Rosenberg Jessica J, Ilagan Charmaine, Nithagon Pichayut, Shafa Shervin, Jennings Joseph J
Department of Internal Medicine, MedStar Georgetown University Hospital, Washington, DC.
Department of Gastroenterology, MedStar Georgetown University Hospital, Washington, DC.
ACG Case Rep J. 2022 Dec 26;9(12):e00938. doi: 10.14309/crj.0000000000000938. eCollection 2022 Dec.
The gastrointestinal (GI) tract is an infrequent site of breast cancer metastasis, but it often poses a diagnostic challenge when it occurs. The symptoms of GI metastases are often nonspecific, and the endoscopic manifestations are variable, requiring tissue biopsies for histologic examination. We report 2 cases of breast cancer metastasizing to the GI tract: a case of human epidermal growth factor receptor 2-positive invasive ductal carcinoma that metastasized to the stomach, a rare location for this histologic subtype, and another case of invasive lobular cell carcinoma that metastasized to the colon with unusual findings of mucosal pallor and edema on colonoscopy.
胃肠道（GI）是乳腺癌转移的罕见部位，但一旦发生，往往会带来诊断挑战。胃肠道转移的症状通常不具有特异性，内镜表现也各不相同，需要进行组织活检以进行组织学检查。我们报告了2例乳腺癌转移至胃肠道的病例：1例人表皮生长因子受体2阳性浸润性导管癌转移至胃，这对于该组织学亚型来说是一个罕见的部位；另一例浸润性小叶癌转移至结肠，结肠镜检查发现有黏膜苍白和水肿等不寻常表现。
