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澳大利亚控制不佳的哮喘患者的医疗支出及其社会人口学和临床预测因素。

Healthcare expenditure and its socio-demographic and clinical predictors in Australians with poorly controlled asthma.

机构信息

Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, United Kingdom.

NIHR Applied Research Collaboration, East of England, United Kingdom.

出版信息

PLoS One. 2023 Jan 5;18(1):e0279748. doi: 10.1371/journal.pone.0279748. eCollection 2023.

Abstract

INTRODUCTION

Asthma has substantial and increasing health and economic burden worldwide. This study aimed to estimate healthcare expenditure and determine the factors that increase expenditure in Australians with poorly controlled asthma.

METHODS

Individuals ≥18 years of age with poorly controlled asthma, as determined by a score ≥1.5 on the Asthma Control Questionnaire, were included in the study. Healthcare utilization costs from medical services and medications were estimated over an average follow-up of 12 months from administratively linked data: the Medicare Benefits Schedule and Pharmaceutical Benefits Scheme. A generalized linear model with gamma distribution and log link was used to predict participants' key baseline characteristics associated with variations in healthcare costs.

RESULTS

A total of 341 participants recruited through community pharmacies were included. The mean (standard deviation, SD) age of participants was 56.6 (SD 17.6) years, and approximately 71% were females. The adjusted average monthly healthcare expenditure per participant was $AU386 (95% CI: 336, 436). On top of the average monthly costs, an incremental expenditure was found for each year increase in age ($AU4; 95% CI: 0.78, 7), being unemployed ($AU201; 95% CI: 91, 311), one unit change in worsening quality of life ($AU35; 95% CI: 9, 61) and being diagnosed with depression and anxiety ($AU171; 95% CI: 36, 306).

CONCLUSIONS

In a cohort of Australian patients, characterized by poor asthma control and co-morbidities individuals impose substantial economic burden in terms of Medicare funded medical services and medications. Programs addressing strategies to improve the quality of life and manage co-morbid anxiety and depression and encourage asthma patients' engagement in clinically tolerable jobs, may result in significant cost savings to the health system.

摘要

简介

哮喘在全球范围内造成了巨大且不断增加的健康和经济负担。本研究旨在评估医疗保健支出,并确定增加澳大利亚控制不佳的哮喘患者支出的因素。

方法

研究纳入了由哮喘控制问卷(Asthma Control Questionnaire)得分≥1.5 确定为控制不佳的哮喘患者,年龄≥18 岁。从管理链接数据(医疗保险福利计划和药品福利计划)中估算了 12 个月平均随访期间医疗服务和药物的医疗保健利用成本。使用具有伽马分布和对数链接的广义线性模型来预测与医疗保健成本变化相关的参与者关键基线特征。

结果

通过社区药房共招募了 341 名参与者。参与者的平均(标准差)年龄为 56.6(17.6)岁,约 71%为女性。每名参与者的平均每月医疗保健支出为 386 澳元(95%CI:336,436)。除了平均每月费用外,还发现年龄每增加 1 岁,支出就会增加 4 澳元(95%CI:0.78,7);失业增加 201 澳元(95%CI:91,311);生活质量恶化一个单位增加 35 澳元(95%CI:9,61);诊断出抑郁和焦虑增加 171 澳元(95%CI:36,306)。

结论

在一组澳大利亚患者中,控制不佳的哮喘和合并症使患者在医疗保险资助的医疗服务和药物方面带来了巨大的经济负担。实施旨在提高生活质量、管理合并焦虑和抑郁以及鼓励哮喘患者从事临床可耐受工作的方案,可能会使医疗保健系统节省大量成本。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e73/9815839/9dec8dbe6892/pone.0279748.g001.jpg

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