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Experiences with radioimmunoassay in the detection of HBsAg in the presence of anti-HBs.

作者信息

Siebke J C

出版信息

J Med Virol. 1978;3(1):35-9. doi: 10.1002/jmv.1890030109.

DOI:10.1002/jmv.1890030109
PMID:366084
Abstract

Interference from anti-HBs present during hepatitis B antigenemia caused the appearance of several false negative reactions in a competition radioimmuno-precipitation procedure. The results indicate that such interference is considerably less in the solid-phase radioimmunoassay (Ausria II) and probably causes few false negative tests. The use of pepsin treatment as a means to destroy interfering antibodies is discussed.

摘要

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