Neppert J, Gerlich W
Zentralbl Bakteriol Orig A. 1979 Oct;245(1-2):8-16.
The prevalence of hepatitis B virus infections was examined in four groups from Liberia using radioimmunoassays for HBsAg, anti-HBs and anti-HBc. At the age of 15-19 years 90% have been infected, at the age of 40 years 100%. In a rubber plantation 30% had HBsAg, in the remaining 3 groups only 13% were HBsAg-positive. In the first group onchocerciasis was also a more frequent finding. However the parasitic infection was not the cause of the HBs-antigenemia. The HBsAg-concentration is mostly lower in the positive Liberians than in German HBsAg-carriers. Apparently the HBV caused frequently latent infections with low production of viral antigens in Liberia.
利用针对乙肝表面抗原(HBsAg)、乙肝表面抗体(抗-HBs)和乙肝核心抗体(抗-HBc)的放射免疫分析法,对来自利比里亚的四组人群进行了乙肝病毒感染率检测。在15至19岁的人群中,90%曾被感染;在40岁的人群中,100%曾被感染。在一个橡胶种植园里,30%的人乙肝表面抗原为阳性,在其余三组中,只有13%的人乙肝表面抗原呈阳性。在第一组中,盘尾丝虫病也是较常见的病症。然而,寄生虫感染并非乙肝抗原血症的病因。利比里亚乙肝表面抗原呈阳性者的乙肝表面抗原浓度大多低于德国乙肝表面抗原携带者。显然,在利比里亚,乙肝病毒常常引发潜伏感染,病毒抗原产量较低。