Department of Hygiene and Public Health, Faculty of Medicine, Osaka Medical and Pharmaceutical University, Takatsuki, Japan.
Research and Development Center, Faculty of Medicine, Osaka Medical and Pharmaceutical University, Takatsuki, Japan.
Geriatr Gerontol Int. 2023 Feb;23(2):103-110. doi: 10.1111/ggi.14530. Epub 2023 Jan 6.
To investigate the effects of high-intensity interval exercise training on microvascular endothelial function among community-dwelling older people.
We analyzed the data from a nonrandomized controlled trial. This study's participants were 48 men (aged 75 ± 5 years; exercise training group, n = 24; control group, n = 24) and 83 women (aged 75 ± 4 years; exercise training group, n = 36; control group, n = 47). The exercise training group underwent a high-intensity interval walking training for 5 months.
In the exercise group, 100% and 91.7% of men and women, respectively, achieved brisk walking times ≥50 min/week. The change in the reactive hyperemia index significantly differed between the groups of men, whereas that in the control group was not significant; however, a significant increase was observed in the exercise training group. Among women, changes in the reactive hyperemia index were not significant in either group; however, for women in the exercise training group, these changes negatively and positively correlated with the change in body mass index (Spearman's rho = -0.342; P = 0.041) and baseline body mass index (rho = 0.362, P = 0.030), respectively. Additionally, the distribution of body mass index was broader in women than in men.
Interval walking training increased the reactive hyperemia index in men rather than in women. A higher variation in baseline body mass index may be associated with no statistical increase in reactive hyperemia index in women. Geriatr Gerontol Int 2023; 23: 103-110.
探讨高强度间歇运动训练对社区老年人微血管内皮功能的影响。
我们分析了一项非随机对照试验的数据。本研究的参与者包括 48 名男性（年龄 75±5 岁；运动训练组 n=24；对照组 n=24）和 83 名女性（年龄 75±4 岁；运动训练组 n=36；对照组 n=47）。运动训练组接受了为期 5 个月的高强度间歇步行训练。
在运动组中，分别有 100%和 91.7%的男性和女性达到了每周快步走时间≥50 分钟。男性组的反应性充血指数变化在组间差异显著，而对照组则不显著；然而，运动训练组观察到显著增加。在女性中，两组的反应性充血指数变化均不显著；然而，对于运动训练组的女性，这些变化与体重指数的变化呈负相关（Spearman 的 rho=-0.342；P=0.041）和基线体重指数（rho=0.362，P=0.030）。此外，女性的体重指数分布比男性更广泛。
间歇步行训练增加了男性而非女性的反应性充血指数。较高的基线体重指数变化可能与女性反应性充血指数无统计学增加有关。老年医学与老年病学国际 2023；23：103-110。
