Holmlund D, Sjödin J G
J Urol. 1978 Dec;120(6):676-7. doi: 10.1016/s0022-5347(17)57325-5.
A randomized prospective double-blind study of the analgesic effect of 50 mg. intravenous indomethacin, a prostaglandin synthesis inhibitor, was done on 47 consecutive patients with acute ureteral colic. The placebo used was 5 mg. intravenous riboflavin because of the same color as indomethacin. Indomethacin provided complete relief in 78 per cent of the cases, while riboflavin provided relief in 30 per cent. The difference is statistically significant. No side effects were observed with indomethacin.
对47例连续的急性输尿管绞痛患者进行了一项随机前瞻性双盲研究，以探讨50毫克静脉注射吲哚美辛（一种前列腺素合成抑制剂）的镇痛效果。所使用的安慰剂是5毫克静脉注射核黄素，因为它与吲哚美辛颜色相同。吲哚美辛在78%的病例中提供了完全缓解，而核黄素在30%的病例中提供了缓解。差异具有统计学意义。未观察到吲哚美辛有副作用。
