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皮下分枝杆菌感染误诊为孢子丝菌病:一例报告。

Scubcutaneous Mycobacterium marinum infection misdiagnosed as sporotrichosis: A case report.

机构信息

Department of Clinical Laboratory.

Department of Dermatology, Hangzhou Third Peoples Hospital, Affiliated Hangzhou Dermatology Hospital, Zhejiang University School of Medicine, Hangzhou, China.

出版信息

Medicine (Baltimore). 2022 Dec 9;101(49):e32220. doi: 10.1097/MD.0000000000032220.

Abstract

INTRODUCTION

Nontuberculous mycobacteria (NTM), are natural inhabitants of natural waters, engineered water systems, and soils. As a consequence of their ubiquitous distribution, humans are surrounded by these opportunistic pathogens.

PATIENT CONCERNS

In this report, we describe a case of scubcutaneous Mycobacterium marinum infection associated with home tropical ornamental fish aquaria. A 43-years-old man reported progressively increasing nodules over his left forearm and hand for more than 7 months.

DIAGNOSIS

Based on NTM culture, pathological examination, identification by gene sequencing and matrix assisted laser desorption ionization time of flight mass spectrometry, the diagnosis of scubcutaneous NTM infection was confirmed.

INTERVENTIONS

The patient was treated with itraconazole for suspected sporotrichosis over 1 month.

OUTCOMES

The patient was treated with oral doxycycline hydrochloride capsules (200 mg/day) for 5 months, the nodules had resolved.

CONCLUSION

Home aquarium environments may serve as a possible source of mycobacteria infection in urban family.

摘要

简介

非结核分枝杆菌(NTM)是天然存在于天然水中、工程化水系统和土壤中的细菌。由于它们无处不在的分布,人类周围都是这些机会性病原体。

患者关注点

在本报告中,我们描述了一例与家庭热带观赏鱼水族馆相关的皮下分枝杆菌感染病例。一名 43 岁男性报告称,其左前臂和手上的结节逐渐增多,持续时间超过 7 个月。

诊断

基于 NTM 培养、病理检查、基因测序和基质辅助激光解吸电离飞行时间质谱鉴定,确诊为皮下分枝杆菌感染。

干预措施

患者因疑似孢子丝菌病接受伊曲康唑治疗超过 1 个月。

结果

患者接受口服盐酸多西环素胶囊(200mg/天)治疗 5 个月后,结节已消退。

结论

家庭水族馆环境可能成为城市家庭中分枝杆菌感染的一个潜在来源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f1d/9750702/405a0f525548/medi-101-e32220-g001.jpg

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