Iargin S V, Pal'tsev M A, Vinogradova O M, Mukharliamova L Iu
Arkh Patol. 1987;49(6):47-54.
The incidence of arterial hypertension (AH) in patients with renal amyloidosis varied with its stage. Thus, AH was encountered in 13% of cases with renal amyloidosis at the proteinuric stage, 15% of those at the nephrotic stage, and 53% of those at the azotemic stage. One determinant of AH at the first two of these stages appears to have been damage to the antihypertensive system of the renal medulla, while the increased rate of AH at the azotemic stage was found to be associated with sodium retention in the body. AH in renal amyloidosis is an unfavorable prognostic factor, for it is conducive to amyloid shrinkage of the kidneys and to chronic renal failure.
肾淀粉样变性患者动脉高血压（AH）的发病率随疾病阶段而异。因此，蛋白尿期肾淀粉样变性患者中AH的发生率为13%，肾病期为15%，氮质血症期为53%。在前两个阶段，AH的一个决定因素似乎是肾髓质抗高血压系统受损，而氮质血症期AH发生率的增加则与体内钠潴留有关。肾淀粉样变性中的AH是一个不良预后因素，因为它会导致肾脏淀粉样变缩小和慢性肾衰竭。
