人体体液中尿囊素和尿酸的测量。体内自由基反应的一个潜在指标？
Measurement of allantoin and uric acid in human body fluids. A potential index of free-radical reactions in vivo?
作者信息
Grootveld M, Halliwell B
机构信息
Department of Biochemistry, King's College (KQC), Strand Campus, London, U.K.
出版信息
Biochem J. 1987 May 1;243(3):803-8. doi: 10.1042/bj2430803.
Abstract
Free-radical attack upon uric acid generates allantoin [Ames, Cathcart, Schwiers & Hochstein (1981) Proc. Natl. Acad. Sci. U.S.A. 78, 6858-6862]. Methods are described for the accurate measurement of uric acid and allantoin in human body fluids. The concentrations of uric acid and allantoin in human serum and synovial fluid are reported. It is suggested that measurement of changes in allantoin concentration may be a useful index of free-radical reactions taking place in vivo.
摘要
尿酸受到自由基攻击会生成尿囊素[艾姆斯、卡特、施维尔斯和霍希斯坦（1981年）《美国国家科学院院刊》78卷，6858 - 6862页]。本文描述了准确测量人体体液中尿酸和尿囊素的方法。报告了人体血清和滑液中尿酸和尿囊素的浓度。有人提出，测量尿囊素浓度的变化可能是体内发生的自由基反应的一个有用指标。
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