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In vitro conversion of pyrazinamide into 5-hydroxypyrazinamide and that of pyrazinoic acid into 5-hydroxypyrazinoic acid by xanthine oxidase from human liver.

作者信息

Yamamoto T, Moriwaki Y, Takahashi S, Hada T, Higashino K

机构信息

Third Department of Internal Medicine, Hyogo College of Medicine, Japan.

出版信息

Biochem Pharmacol. 1987 Oct 1;36(19):3317-8. doi: 10.1016/0006-2952(87)90654-x.

DOI:10.1016/0006-2952(87)90654-x
PMID:3663245
Abstract
摘要

相似文献

1
In vitro conversion of pyrazinamide into 5-hydroxypyrazinamide and that of pyrazinoic acid into 5-hydroxypyrazinoic acid by xanthine oxidase from human liver.人肝脏中的黄嘌呤氧化酶将吡嗪酰胺体外转化为5-羟基吡嗪酰胺以及将吡嗪酸体外转化为5-羟基吡嗪酸。
Biochem Pharmacol. 1987 Oct 1;36(19):3317-8. doi: 10.1016/0006-2952(87)90654-x.
2
Study of the metabolism of pyrazinamide using a high-performance liquid chromatographic analysis of urine samples.采用高效液相色谱法分析尿液样本对吡嗪酰胺代谢情况的研究。
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3
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6
Study of urinary pyrazinamide metabolites and their action on the renal excretion of xanthine and hypoxanthine in a xanthinuric patient.黄嘌呤尿症患者尿液中吡嗪酰胺代谢产物及其对黄嘌呤和次黄嘌呤肾排泄作用的研究。
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8
[Microdetermination of pyrazinamide and its metabolites (pyrazinoic acid, 5-hydroxypyrazinoic acid, 5-hydroxypyrazinamide and pyrazinuric acid) in plasma and urine with liquid chromatography].[用液相色谱法微量测定血浆和尿液中的吡嗪酰胺及其代谢产物（吡嗪酸、5-羟基吡嗪酸、5-羟基吡嗪酰胺和吡嗪尿酸）]
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Metabolic disposition of pyrazinamide in the rat: identification of a novel in vivo metabolite common to both rat and human.
Biopharm Drug Dispos. 1987 Jul-Aug;8(4):307-18. doi: 10.1002/bdd.2510080402.

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