Barnes N, Cartwright R A, O'Brien C, Roberts B, Richards I D, Bird C C
University Department of Community Medicine, Leeds.
Br J Cancer. 1987 Aug;56(2):169-72. doi: 10.1038/bjc.1987.179.
The possibilities of clustering between those electoral wards which display higher than expected incidences of cases of the lymphomas occurring between 1978 and 1982 are examined. Clusters are defined as being those wards with cases in excess (at a probability of less than 10%) which are geographically adjacent to each other. A separate analysis extends the definition of cluster to include high incidence wards that are adjacent or separated by one other ward. The results indicate that many high incidence lymphoma wards do occur close together and when computer simulations are used to compute expected results, many of the observed results are shown to be highly improbable both in the overall number of clustering wards and in the largest number of wards comprising a 'cluster'.
对1978年至1982年间淋巴瘤病例发生率高于预期的那些选区之间出现聚集的可能性进行了研究。聚集区被定义为病例数超出预期(概率小于10%)且在地理上彼此相邻的选区。另一项分析将聚集区的定义扩展到包括相邻或被另一个选区隔开的高发病选区。结果表明,许多高发病的淋巴瘤选区确实彼此相邻,当使用计算机模拟来计算预期结果时,无论是在聚集选区的总数还是在构成“聚集区”的最大选区数量方面,许多观察到的结果都显示出极不可能。