Triasih Rina, Setyowireni Dwikisworo, Nurani Neti, Setyati Amalia
Department of Pediatrics, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada /Dr. Sardjito Hospital, Yogyakarta, Indonesia.
J Asthma Allergy. 2023 Jan 5;16:23-32. doi: 10.2147/JAA.S392733. eCollection 2023.
Childhood asthma in developing countries has been increasing, but underdiagnosed and undertreated. We reported prevalence, management, and risk factors of asthma among school-age children in Yogyakarta, Indonesia.
We recruited children aged 6-7 years and 13-14 years attending schools in all districts in Yogyakarta, Indonesia. The schools were randomly selected via cluster random sampling. We used the Indonesian version of the Global Asthma Network (GAN) questionnaire, and the methodology employed by this study was in accordance with the GAN's protocol.
A total of 2106 children aged 6-7 years and 3142 adolescents aged 13-14 years were eligible for analysis. The prevalence of current wheeze in children and adolescents was similar, which was 4.6%. Inhalation therapy was reported in <30% of those with asthma. Risk factors for current wheeze in children were wheezing in infancy period, ever had pneumonia, the house was passed by trucks every day, and fast-food consumption in the previous 12 months; whereas exclusive breastfeeding for more than 6 months decreased the risk of current wheeze. In adolescence, obesity, consumption of fast food once or twice a week, and paracetamol in the previous 12 months increased the risk of current wheeze.
The prevalence of current wheeze in children and adolescents in Indonesia was quite low. The use of inhalation therapy was limited. Respiratory problems during infancy, environmental, and nutritional factors play a role in the development of asthma.
发展中国家儿童哮喘发病率一直在上升,但存在诊断不足和治疗不足的情况。我们报告了印度尼西亚日惹学龄儿童哮喘的患病率、管理情况及风险因素。
我们招募了印度尼西亚日惹所有地区6至7岁和13至14岁的在校儿童。通过整群随机抽样随机选择学校。我们使用了印度尼西亚版的全球哮喘网络(GAN)问卷,本研究采用的方法符合GAN的方案。
共有2106名6至7岁儿童和3142名13至14岁青少年符合分析条件。儿童和青少年当前喘息的患病率相似,为4.6%。报告显示,<30%的哮喘患者接受了吸入治疗。儿童当前喘息的风险因素包括婴儿期喘息、曾患肺炎、房屋每天有卡车经过以及过去12个月内食用快餐;而纯母乳喂养超过6个月可降低当前喘息的风险。在青少年中,肥胖、每周食用一到两次快餐以及过去12个月内服用对乙酰氨基酚会增加当前喘息的风险。
印度尼西亚儿童和青少年当前喘息的患病率相当低。吸入治疗的使用有限。婴儿期的呼吸道问题、环境和营养因素在哮喘的发展中起作用。