Scarone S, Gambini O, Häfele E, Bellodi L, Smeraldi E
Department of Psychiatry, University of Milan Medical School, Italy.
Biol Psychol. 1987 Jun;24(3):253-9. doi: 10.1016/0301-0511(87)90006-8.
This preliminary study evaluated the simultaneous presence of abnormalities in the regulation of eye-tracking and neuropsychological tests performance (tactile extinction) in a sample of schizophrenic patients. Both those measures of central malfunctioning appears to be quite specific to schizophrenic disorders and more related to the trait, rather than state characteristics. Even though preliminary, the results indicate a significant relationship between abnormalities in SPEM regulation and the distribution of tactile abnormalities, with more left-side extinguishing patients showing abnormal SPEMs. Some interpretations of the findings are given in the context of current hypotheses on the neurofunctional abnormalities of schizophrenics.
这项初步研究评估了在一组精神分裂症患者样本中,眼动追踪调节异常与神经心理测试表现(触觉消退)异常同时存在的情况。这两种中枢功能障碍的测量指标似乎对精神分裂症具有相当的特异性,并且更多地与特质相关,而非状态特征。尽管是初步研究,但结果表明平稳视动眼震调节异常与触觉异常分布之间存在显著关系,左侧触觉消退的患者表现出更多的异常平稳视动眼震。研究结果的一些解释是在当前关于精神分裂症神经功能异常的假说背景下给出的。