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韩国红参通过上调猪的CD4CD8 T细胞和NK细胞活性来调节免疫功能。

Korean Red Ginseng modulates immune function by upregulating CD4CD8 T cells and NK cell activities on porcine.

作者信息

Alam Md Jahangir, Hossain Mohammad Amjad, Bhilare Kiran D, Kang Chang-Won, Kim Jong-Hoon

机构信息

College of Veterinary Medicine, Biosafety Research Institute, Jeonbuk National University, Iksan, Republic of Korea.

出版信息

J Ginseng Res. 2023 Jan;47(1):155-158. doi: 10.1016/j.jgr.2022.10.002. Epub 2022 Oct 18.

DOI:10.1016/j.jgr.2022.10.002
PMID:36644387
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9834015/
Abstract

In the present study, we investigated whether treatment with KRG improve the parameters of immune activity such as the cytotoxicity, populations of CD4 CD8T cell, CD3CD172CD8 NK cell and CD172 monocyte as well as natural cytotoxicity receptors such as Nkp46, Nkp44, Nkp30. In results, KRG significantly increased these immune activities. These results indicate that KRG has distinct immune-enhancing effects by increasing the roles of T cells and NK cell in porcine.

摘要

在本研究中,我们调查了人参皂苷rg处理是否能改善免疫活性参数,如细胞毒性、CD4 CD8T细胞、CD3CD172CD8 NK细胞和CD172单核细胞的数量,以及自然细胞毒性受体如Nkp46、Nkp44、Nkp30。结果显示,人参皂苷rg显著增强了这些免疫活性。这些结果表明,人参皂苷rg通过增强猪体内T细胞和NK细胞的作用具有明显的免疫增强效果。

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本文引用的文献

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Vaccines (Basel). 2020 Dec 11;8(4):755. doi: 10.3390/vaccines8040755.
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Effect of ginseng polysaccharides on NK cell cytotoxicity in immunosuppressed mice.人参多糖对免疫抑制小鼠自然杀伤细胞细胞毒性的影响。
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Red ginseng and vitamin C increase immune cell activity and decrease lung inflammation induced by influenza A virus/H1N1 infection.
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J Ginseng Res. 2024 Sep;48(5):504-510. doi: 10.1016/j.jgr.2024.05.007. Epub 2024 May 31.
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Int J Mol Sci. 2023 Mar 24;24(7):6119. doi: 10.3390/ijms24076119.
红参和维生素C可增强免疫细胞活性,并减轻甲型流感病毒/H1N1感染所致的肺部炎症。
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Korean red ginseng extract exhibits neuroprotective effects through inhibition of apoptotic cell death.韩国红参提取物通过抑制凋亡性细胞死亡发挥神经保护作用。
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