Poyser Tracy-Ann, Gbadebo Damilola, Krebs Jacob, Brock Jordan M, Robinson Eric
Internal Medicine, Unity Health-White County Medical Center, Searcy, USA.
Cardiology, Unity Health-White County Medical Center, Searcy, USA.
Cureus. 2024 Apr 25;16(4):e58979. doi: 10.7759/cureus.58979. eCollection 2024 Apr.
Infective endocarditis (IE) remains a formidable challenge in clinical practice due to several causative agents, each presenting with unique diagnostic and therapeutic dilemmas. , a coagulase-negative, catalase-positive Gram-positive coccus, has recently emerged as an uncommon but increasingly recognized pathogen in the cause of IE. This case report highlights the clinical characteristics, risk factors, and challenges associated with -induced IE. We conducted a comprehensive literature review and identified several case reports on as a causative agent. Due to its indolent nature and the subtle presentation of symptoms, along with its ability to form biofilms, delayed diagnosis of is often seen, thereby emphasizing the need for heightened clinical suspicion. The predisposing factors for infection include underlying cardiac abnormalities, prosthetic heart valves, and immunocompromised states. Additionally, antimicrobial susceptibility patterns and optimal treatment strategies remain unclear, warranting further investigation. This abstract presents the case of a 75-year-old male with IE secondary to on a prosthetic mitral valve. We aim to highlight the need for increased awareness among clinicians to facilitate early recognition and prompt initiation of targeted therapeutic interventions. Unraveling the intricacies of pathogenicity is crucial for refining diagnostic approaches and optimizing patient outcomes.
感染性心内膜炎(IE)在临床实践中仍然是一个严峻的挑战,因为有多种致病因素,每种因素都带来独特的诊断和治疗难题。凝固酶阴性、过氧化氢酶阳性的革兰氏阳性球菌最近已成为IE病因中一种不常见但越来越受认可的病原体。本病例报告强调了与该菌引起的IE相关的临床特征、危险因素和挑战。我们进行了全面的文献综述,并确定了几例关于该菌作为病原体的病例报告。由于其病程隐匿、症状表现不明显,以及形成生物膜的能力,该菌感染的诊断往往延迟,从而强调了提高临床怀疑度的必要性。该菌感染的易感因素包括潜在的心脏异常、人工心脏瓣膜和免疫功能低下状态。此外,抗菌药物敏感性模式和最佳治疗策略仍不明确,需要进一步研究。本摘要介绍了一名75岁男性因人工二尖瓣感染该菌继发IE的病例。我们旨在强调临床医生需要提高认识,以便于早期识别并迅速启动有针对性的治疗干预措施。阐明该菌致病性的复杂性对于完善诊断方法和优化患者治疗结果至关重要。