慢性下腰痛患者超声回声强度与基于水脂成像的 MRI 多裂肌肌内脂肪比较。

Comparison of multifidus muscle intramuscular fat by ultrasound echo intensity and fat-water based MR images in individuals with chronic low back pain.

机构信息

Concordia University, Department Health Kinesiology and Applied Physiology, Montreal, Quebec, Canada.

Department of Electrical and Computer Engineering, Concordia University, Montreal, Quebec, Canada; PERFORM Centre, Concordia University, Montreal, Quebec, Canada.

出版信息

Musculoskelet Sci Pract. 2023 Feb;63:102717. doi: 10.1016/j.msksp.2023.102717. Epub 2023 Jan 5.

DOI:10.1016/j.msksp.2023.102717

PMID:36658047

Abstract

PURPOSE

The aim of this observational cross-sectional study was to examine correlations of intramuscular fat content in lumbar multifidus (LM) by comparing muscle echo intensity (EI) and percent fat signal fraction (%FSF) generated from ultrasound (US) and magnetic resonance (MR) images, respectively.

METHODS

MRI and US images from 25 participants (16 females, 9 males) selected from a cohort of patients with chronic low back pain (CLBP) were used. Images were acquired bilaterally, at the L4 and L5 levels (e.g., 4 sites). EI measurements were acquired by manually tracing the cross-sectional border of LM. Mean EI of three US images per site were analyzed (e.g., raw EI). A correction factor for subcutaneous fat thickness (SFT) was also calculated and applied (e.g., corrected EI). Corresponding fat and water MR images were used to acquire %FSF measurements. Intra-rater reliability was assessed by intraclass coefficients (ICC). Pearson correlations and simple linear regression were used to assess the relationship between %FSF, raw EI and corrected EI measurements.

RESULTS

The intra-rater ICCs for all measurements were moderate to excellent. Correlations between %FSF vs. raw EI and corrected EI were moderate to strong (0.40 < r < 0.52) and (0.40 < r < 0.51), respectively. Moderate correlations between SFT and EI were also identified.

CONCLUSION

US is a low-cost, non-invasive, accessible, and reliable method to examine muscle composition, and presents a promising solution for assessing and monitoring the effect of different treatment options for CLBP in clinical settings.

摘要

目的

本观察性横断面研究旨在通过比较超声（US）和磁共振（MR）图像分别生成的腰椎多裂肌（LM）内肌肉回声强度（EI）和脂肪信号分数百分比（%FSF），来检测 LM 内的肌肉脂肪含量相关性。

方法

从慢性下腰痛（CLBP）患者队列中选择了 25 名参与者（16 名女性，9 名男性）的 MRI 和 US 图像。在 L4 和 L5 水平（例如，4 个部位）分别进行双侧图像采集。通过手动追踪 LM 的横截面边界获取 EI 测量值。对每个部位的 3 张 US 图像的平均 EI 进行分析（例如，原始 EI）。还计算并应用了皮下脂肪厚度（SFT）的校正因子（例如，校正 EI）。使用相应的脂肪和水 MR 图像获取 %FSF 测量值。通过组内相关系数（ICC）评估内部评估者的可靠性。使用 Pearson 相关和简单线性回归评估 %FSF、原始 EI 和校正 EI 测量值之间的关系。