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母鸡的卵巢肿瘤。

Ovarian tumors of the hen.

作者信息

Fredrickson T N

机构信息

Department of Pathobiology, University of Connecticut, Storrs 06268.

出版信息

Environ Health Perspect. 1987 Aug;73:35-51. doi: 10.1289/ehp.877335.

DOI:10.1289/ehp.877335
PMID:3665870
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1474556/
Abstract

Present available information regarding ovarian tumors in hens is incomplete in most aspects, and this lack of knowledge hampers use of hens as models for study of ovarian cancer. A study of 466 hens ranging from 2 to 7 years of age and covering a period of more than 3 years has provided much needed information relative to reproductive tract neoplasia. On the basis of this study, it is apparent that hens have a high rate of ovarian tumors, but that such tumors are uncommon in hens less than 2 years of age. Adenocarcinomas with a high degree of morphologic variability are the most common ovarian tumors in hens. Hormonal imbalance does not appear to be a factor in the development of these adenocarcinomas. Steroidogenic and morphologically distinctive granulosa cell tumors originating from follicles in atrophic ovaries represent another common ovarian tumor type. Unique to the hen are oviductal adenocarcinomas. These tumors arise from the albumin-secreting glands of the oviduct, occur with relatively high frequency, and must be differentiated from ovarian adenocarcinomas.

摘要

目前关于母鸡卵巢肿瘤的现有信息在大多数方面并不完整，而这种知识的匮乏阻碍了将母鸡用作卵巢癌研究模型。一项对466只年龄在2至7岁之间、历时3年多的母鸡的研究，提供了与生殖道肿瘤相关的急需信息。基于这项研究，很明显母鸡的卵巢肿瘤发生率很高，但此类肿瘤在2岁以下的母鸡中并不常见。形态学变异程度高的腺癌是母鸡中最常见的卵巢肿瘤。激素失衡似乎不是这些腺癌发生的一个因素。起源于萎缩卵巢卵泡的具有类固醇生成和形态学特征的颗粒细胞瘤是另一种常见的卵巢肿瘤类型。输卵管腺癌是母鸡所特有的。这些肿瘤起源于输卵管的白蛋白分泌腺，发生频率相对较高，必须与卵巢腺癌相鉴别。

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