Gevaert Philippe, De Craemer Jarno, Bachert Claus, Blauwblomme Manon, Chaker Adam, Cingi Cemal, Hellings Peter W, Hopkins Claire, Hox Valérie, Fokkens Wytske J, Klimek Ludger, Lund Valerie, Mösges Ralph, Mullol Joaquim, Pfaar Oliver, Scadding Glenis, Tomazic Peter Valentin, Van Zele Thibaut, Vlaminck Stephan, Wagenmann Martin, Toppila-Salmi Sanna, Alobid Isam
Upper Airways Research Laboratory, Department of Otorhinolaryngology, Ghent University, Ghent, Belgium.
First Affiliated Hospital, Sun Yat-sen University, International Airway Research Center, Guangzhou, China.
Allergy. 2023 Apr;78(4):912-922. doi: 10.1111/all.15650. Epub 2023 Feb 3.
Nasal endoscopy is not only used for the diagnosis of chronic rhinosinusitis with nasal polyps (CRSwNP), but also for monitoring the response to therapy playing an important role in both daily practice and research. In contrast to patient-reported outcomes, endoscopic nasal polyp scoring by independent blinded readers is an objective measurement, not influenced by the placebo effect. It is safer and cheaper compared with computed tomography imaging and therefore, better suited for regular assessments of the extent of the disease. Since the early 90s, a variety of endoscopic staging methods have been proposed and used in clinical research, making it hard to compare results from different studies. This paper resulted from a task force with experts in the field of CRSwNP, originated by the Ear, Nose and Throat section of the European Academy of Allergy and Clinical Immunology and aims to provide a unified endoscopic NP scoring system that can serve as a reference standard for researchers, but also as a useful tool for practitioners involved in the management of CRSwNP.
鼻内镜检查不仅用于诊断伴有鼻息肉的慢性鼻-鼻窦炎(CRSwNP),还用于监测治疗反应,在日常实践和研究中都发挥着重要作用。与患者报告的结果不同,由独立的盲法读者进行的鼻息肉内镜评分是一种客观测量,不受安慰剂效应影响。与计算机断层扫描成像相比,它更安全、成本更低,因此更适合对疾病范围进行定期评估。自20世纪90年代初以来,已提出多种内镜分期方法并用于临床研究,这使得不同研究结果难以比较。本文由欧洲变态反应和临床免疫学会耳鼻喉科发起的一个由CRSwNP领域专家组成的特别工作组撰写,旨在提供一个统一的鼻息肉内镜评分系统,该系统既可以作为研究人员的参考标准,也可以作为参与CRSwNP管理的从业者的有用工具。