Jacobowitz D M, O'Donohue T L
Proc Natl Acad Sci U S A. 1978 Dec;75(12):6300-4. doi: 10.1073/pnas.75.12.6300.
alpha-Melanocyte stimulating hormone (alpha-melanotropin) immunofluorescence was observed in rat brain by means of a highly specific and well-characterized antibody. The hormone was contained in arcuate nucleus cell bodies and in varicose fibers. Dense populations of hormone-containing fibers were present in the septum, the nucleus interstitialis stria terminalis, and the medial preoptic, anterior hypothalamic, dorsomedial, and periventricular nuclei. Moderate numbers of fibers were seen in the paraventricular and arcuate nuclei, the amygdala, the region of the tractus diagonalis, the mammillary body, the central gray, the cuneiform nucleus, and the nucleus of the solitary tract. There is an interesting correlation of alpha-melanocyte stimulating hormone fibers with regions of noradrenergic axonal projections and terminal fields.
通过一种高度特异性且特性明确的抗体，在大鼠脑中观察到了α-黑素细胞刺激素（α-促黑素）免疫荧光。该激素存在于弓状核细胞体和曲张纤维中。在隔区、终纹床核、内侧视前核、下丘脑前核、背内侧核和室周核中存在大量含激素纤维。在室旁核和弓状核、杏仁核、斜角带区域、乳头体、中央灰质、楔状核和孤束核中可见中等数量的纤维。α-黑素细胞刺激素纤维与去甲肾上腺素能轴突投射区域和终末场之间存在有趣的相关性。
