硫（VI）氟化物在生物分子和药物化学中的应用。
Sulfur(VI) fluorides as tools in biomolecular and medicinal chemistry.
机构信息
Department of Chemistry, Pomona College, Claremont, California 91711, USA.
Pfizer Worldwide Research, Development, Groton, Connecticut 06340, USA.
出版信息
Org Biomol Chem. 2023 Feb 15;21(7):1356-1372. doi: 10.1039/d2ob01891h.
Abstract
Recent advances in the synthesis of sulfur(VI)-fluorides has enabled incredible growth in their application in biomolecular chemistry. This review aims to serve as a primer highlighting synthetic strategies toward a diversity of S(VI) fluorides and their application in chemical biology, bioconjugation, and medicinal chemistry.
摘要
近年来，硫（VI）氟化物的合成取得了进展，使其在生物分子化学中的应用得到了极大的发展。本文旨在作为一个入门指南，重点介绍各种 S(VI)氟化物的合成策略及其在化学生物学、生物缀合和药物化学中的应用。
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