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F波在评估尿毒症性多发性神经病中的应用:持续非卧床腹膜透析应用后的长期研究

F-waves in evaluating uremic polyneuropathy: a long-term study after the application of continuous ambulatory peritoneal dialysis.

作者信息

Peioglou-Harmoussi S, Dimitriadis A, Antoniou S, Noitsi-Michali F, Logothetis J

机构信息

Second Department of Neurology, University of Thessaloniki, Greece.

出版信息

Funct Neurol. 1987 Apr-Jun;2(2):195-205.

PMID:3666549
Abstract

Electrophysiological parameters were studied in 8 patients with end-stage chronic renal failure (CRF). The patients had complete evaluations of the state of CRF, clinical neurological examinations and EMG studies, performed before starting continuous ambulatory peritoneal dialysis (CAPD) as well as 10 days, 2 months and 6 months after initiation of CAPD treatment. All the conventional electrophysiological parameters studied (motor and sensory conduction velocities, terminal latencies, muscle and nerve action potentials) had a tendency to shift towards normal values, the effect being more pronounced in the upper limbs. F-wave maximum and minimum latencies improved quickly in the upper limbs, but very slowly, if at all, in the lower limbs. F-wave frequency became normal in 82% of the median and ulnar nerves, in 75% of the tibial nerves and remained unchanged in the peroneal nerves. F-wave identically, as represented by the "test of multiplicity", showed a general improvement in all nerves, including the peroneal. Studies of F-wave parameters, in addition to improving the diagnostic results, provide a more sensitive method, whereby the effects of CAPD can be examined quantitatively.

摘要

对8例终末期慢性肾衰竭(CRF)患者的电生理参数进行了研究。这些患者在开始持续非卧床腹膜透析(CAPD)之前以及CAPD治疗开始后的10天、2个月和6个月,对CRF状态进行了全面评估,进行了临床神经学检查和肌电图研究。所有研究的常规电生理参数(运动和感觉传导速度、终末潜伏期、肌肉和神经动作电位)都有向正常值偏移的趋势,在上肢更为明显。F波最大和最小潜伏期在上肢改善迅速,但在下肢改善非常缓慢,甚至根本没有改善。82%的正中神经和尺神经、75%的胫神经的F波频率恢复正常,腓总神经的F波频率保持不变。由“多重性测试”表示的F波同样在所有神经(包括腓总神经)中总体上有所改善。F波参数的研究除了改善诊断结果外,还提供了一种更敏感的方法,通过该方法可以定量检查CAPD的效果。

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引用本文的文献

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Polyneuropathy in hemodialysis patients: the most sensitive electrophysiological parameters and dialysis adequacy.血液透析患者的多发性神经病:最敏感的电生理参数及透析充分性
Wien Klin Wochenschr. 2006;118 Suppl 2:29-34. doi: 10.1007/s00508-006-0547-8.