Nakatani Sara, Yamamoto Kohei, Ohtsuki Tomoaki
Graduate School of Science and Technology, Keio University, Yokohama 223-8522, Kanagawa, Japan.
Department of Information and Computer Science, Keio University, Yokohama 223-8522, Kanagawa, Japan.
Bioengineering (Basel). 2022 Dec 30;10(1):48. doi: 10.3390/bioengineering10010048.
Arrhythmia is one of the causes of sudden infant death, and it is very important to detect fetal arrhythmia for fetal well-being. Fetal electrocardiogram (FECG) is one of the methods to detect a heartbeat. Fetal arrhythmia can be detected based on the heartbeat detection results from FECG signals such as heartbeat intervals. However, the accuracy of arrhythmia detection easily degrades depending on the accuracy of heartbeat detection. In this paper, we propose a deep learning-based fetal arrhythmia detection method using FECG signals. Recently, arrhythmia detection methods using adult ECG signals have achieved a high arrhythmia detection accuracy based on deep learning. Motivated by this fact, in the proposed method, the acquired FECG signals are segmented, and the segments are input into a deep learning model that classifies them into normal or arrhythmia ones. Based on the classification results of multiple segments, a subject is judged as a healthy or arrhythmia subject. Each segment of the training data is divided into three categories based on the estimated heartbeat interval: (i) normal, (ii) arrhythmia, and (iii) a segment that could be both normal and arrhythmic. Only segments labeled as normal or arrhythmia are used for training a deep learning model to achieve a higher classification accuracy of the model. Through these procedures, the proposed method detects fetal arrhythmia with fewer effects of heartbeat detection results. The experimental results show that the proposed method achieves 96.2% accuracy, 100% specificity, and 100% recall, improving the values of conventional methods based on heartbeat detection and feature detection.
心律失常是婴儿猝死的原因之一,检测胎儿心律失常对胎儿健康非常重要。胎儿心电图(FECG)是检测心跳的方法之一。可以根据FECG信号的心跳检测结果(如心跳间期)来检测胎儿心律失常。然而,心律失常检测的准确性很容易因心跳检测的准确性而降低。在本文中,我们提出了一种基于深度学习的利用FECG信号检测胎儿心律失常的方法。最近,利用成人心电图信号的心律失常检测方法基于深度学习实现了较高的心律失常检测准确率。受这一事实的启发,在所提出的方法中,对采集到的FECG信号进行分割,并将这些片段输入到一个深度学习模型中,该模型将它们分类为正常或心律失常的片段。基于多个片段的分类结果,判断一个受试者是健康还是患有心律失常。训练数据的每个片段根据估计的心跳间期分为三类:(i)正常,(ii)心律失常,(iii)可能既是正常又是心律失常的片段。仅将标记为正常或心律失常的片段用于训练深度学习模型,以实现更高的模型分类准确率。通过这些步骤,所提出的方法在心跳检测结果的影响较小的情况下检测胎儿心律失常。实验结果表明,所提出的方法实现了96.2%的准确率、100%的特异性和100%的召回率,提高了基于心跳检测和特征检测的传统方法的值。