Graduate School of Agriculture, Kyoto University, Kyoto 606-8502, Japan.
Division of Meat Animal and Poultry Research, Institute of Livestock and Grassland Science, Tsukuba 305-0901, Japan.
Genes (Basel). 2022 Dec 22;14(1):24. doi: 10.3390/genes14010024.
We fitted statistical models, which assumed single-nucleotide polymorphism (SNP) marker effects differing across the fattened steers marketed into different prefectures, to the records for cold carcass weight (CW) and marbling score (MS) of 1036, 733, and 279 Japanese Black fattened steers marketed into Tottori, Hiroshima, and Hyogo prefectures in Japan, respectively. Genotype data on 33,059 SNPs was used. Five models that assume only common SNP effects to all the steers (model 1), common effects plus SNP effects differing between the steers marketed into Hyogo prefecture and others (model 2), only the SNP effects differing between Hyogo steers and others (model 3), common effects plus SNP effects specific to each prefecture (model 4), and only the effects specific to each prefecture (model 5) were exploited. For both traits, slightly lower values of residual variance than that of model 1 were estimated when fitting all other models. Estimated genetic correlation among the prefectures in models 2 and 4 ranged to 0.53 to 0.71, all <0.8. These results might support that the SNP effects differ among the prefectures to some degree, although we discussed the necessity of careful consideration to interpret the current results.
我们拟合了统计模型，这些模型假设单一核苷酸多态性（SNP）标记效应在不同地区的育肥牛中有所不同，这些模型适用于记录分别在日本鸟取、广岛和兵库三个县销售的 1036、733 和 279 头日本黑育肥牛的冷胴体重量（CW）和大理石花纹评分（MS）。使用了 33059 个 SNP 的基因型数据。我们利用了 5 种模型，这些模型假设所有育肥牛的 SNP 效应都是相同的（模型 1）、育肥牛的 SNP 效应在兵库县销售的育肥牛和其他育肥牛之间存在差异（模型 2）、只有兵库县育肥牛和其他育肥牛之间存在差异的 SNP 效应（模型 3）、每个县都具有特异性的 SNP 效应（模型 4）和只有每个县都具有特异性的 SNP 效应（模型 5）。对于这两个性状，当拟合所有其他模型时，估计的残差方差值略低于模型 1。在模型 2 和 4 中，各县之间的遗传相关性估计值在 0.53 到 0.71 之间，均<0.8。这些结果可能表明，SNP 效应在一定程度上存在差异，尽管我们讨论了需要谨慎考虑以解释当前的结果。
