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乳酸杆菌如何寻找并抵达阴道?

How Do Lactobacilli Search and Find the Vagina?

作者信息

Reid Gregor

机构信息

Departments of Microbiology and Immunology, and Surgery, University of Western Ontario, London, ON N6A 3K7, Canada.

Lawson Health Research Institute, London, ON N6A 4V2, Canada.

出版信息

Microorganisms. 2023 Jan 6;11(1):148. doi: 10.3390/microorganisms11010148.

DOI:10.3390/microorganisms11010148
PMID:36677440
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9861324/
Abstract

With the advent of omics technology and the improved culturing of anaerobic microbes, there is a good understanding of the microorganisms present in a healthy and diseased vagina. This has led to the identification of a select few species associated with health. However, the origin of these species and how they reach the vagina remains unclear, as does their timing of colonization. In an effort to create badly needed therapies for women, these gaps in knowledge need to be addressed.

摘要

随着组学技术的出现以及厌氧微生物培养技术的改进,人们对健康和患病阴道中存在的微生物有了很好的了解。这导致了一些与健康相关的特定物种的鉴定。然而,这些物种的起源、它们如何到达阴道以及它们的定植时间仍不清楚。为了努力为女性创造急需的治疗方法,这些知识空白需要得到解决。

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本文引用的文献

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Microbiome. 2022 Nov 26;10(1):201. doi: 10.1186/s40168-022-01400-1.
2
Lactic acid from vaginal microbiota enhances cervicovaginal epithelial barrier integrity by promoting tight junction protein expression.阴道微生物群产生的乳酸通过促进紧密连接蛋白表达增强宫颈阴道上皮屏障完整性。
Microbiome. 2022 Aug 31;10(1):141. doi: 10.1186/s40168-022-01337-5.
3
Clustering Analysis of the Multi-Microbial Consortium by Species Against Vaginal Dysbiosis Among Ecuadorian Women.基于物种的多微生物联合体对厄瓜多尔妇女阴道失调的聚类分析。
Front Cell Infect Microbiol. 2022 May 11;12:863208. doi: 10.3389/fcimb.2022.863208. eCollection 2022.
4
Towards a deeper understanding of the vaginal microbiota.深入了解阴道微生物组。
Nat Microbiol. 2022 Mar;7(3):367-378. doi: 10.1038/s41564-022-01083-2. Epub 2022 Mar 4.
5
Interstrain Variability of Human Vaginal for Metabolism of Biogenic Amines and Antimicrobial Activity against Urogenital Pathogens.人阴道内菌株间生物胺代谢和抗泌尿生殖道病原体的抗菌活性的变异性。
Molecules. 2021 Jul 27;26(15):4538. doi: 10.3390/molecules26154538.
6
Vaginotypes of the human vaginal microbiome.人类阴道微生物组的阴道类型。
Environ Microbiol. 2021 Mar;23(3):1780-1792. doi: 10.1111/1462-2920.15441. Epub 2021 Feb 28.
7
Distinct Immune Responses Elicited From Cervicovaginal Epithelial Cells by Lactic Acid and Short Chain Fatty Acids Associated With Optimal and Non-optimal Vaginal Microbiota.乳酸和短链脂肪酸引起的宫颈阴道上皮细胞的不同免疫反应与最佳和非最佳阴道微生物群有关。
Front Cell Infect Microbiol. 2020 Jan 10;9:446. doi: 10.3389/fcimb.2019.00446. eCollection 2019.
8
Comparative genomics of human Lactobacillus crispatus isolates reveals genes for glycosylation and glycogen degradation: implications for in vivo dominance of the vaginal microbiota.比较人乳杆菌crispatus 分离株的基因组学揭示了糖基化和糖原降解的基因:对阴道微生物群在体内优势的影响。
Microbiome. 2019 Mar 29;7(1):49. doi: 10.1186/s40168-019-0667-9.
9
Comparative Genomic and Phenotypic Analysis of the Vaginal Probiotic GR-1.阴道益生菌GR-1的比较基因组学与表型分析
Front Microbiol. 2018 Jun 15;9:1278. doi: 10.3389/fmicb.2018.01278. eCollection 2018.
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