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在萝卜中氯氟氰菊酯及其代谢物的残留行为和膳食风险评估。

Residual Behavior and Dietary Risk Assessment of Chlorfenapyr and Its Metabolites in Radish.

机构信息

Institute of Plant Protection and Agro-Product Safety, Anhui Academy of Agricultural Sciences, Hefei 230031, China.

Key Laboratory of Agro-Product Safety Risk Evaluation (Hefei), Ministry of Agriculture, Hefei 230031, China.

出版信息

Molecules. 2023 Jan 6;28(2):580. doi: 10.3390/molecules28020580.

DOI:10.3390/molecules28020580
PMID:36677638
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9866042/
Abstract

Chlorfenapyr, as a highly effective and low-toxicity insect growth regulation inhibitor, has been used to control cross-cruciferous vegetable pests. However, the pesticide residue caused by its application threatens human health. In this paper, the residue digestion and final residue of chlorfenapyr in radish were studied in a field experiment. The results of the dynamic digestion test showed that the half-life of chlorfenapyr in radish leaves ranged from 6.0 to 6.4 days, and the digestion rate was fast. The median residual values of chlorfenapyr in radish and radish leaves at 14 days after treatment were 0.12 and 3.92 mg/kg, respectively. The results of the dietary intake risk assessment showed that the national estimated daily intake (NEDI) of chlorfenapyr in various populations in China were 0.373 and 5.66 µg/(kg bw·d), respectively. The risk entropy (RQ) was 0.012 and 0.147, respectively, indicating that the chronic dietary intake risk of chlorfenapyr in radish was low. The results of this study provided data support and a theoretical basis for guiding the scientific use of chlorfenapyr in radish production and evaluating the dietary risk of chlorfenapyr in vegetables.

摘要

氯氟氰菊酯作为一种高效低毒的昆虫生长调节剂,已被用于防治十字花科蔬菜害虫。但由于其使用所带来的农药残留问题威胁着人类健康。本研究采用田间试验的方法,研究了氯氟氰菊酯在萝卜中的消解动态和最终残留。动态消解试验结果表明,氯氟氰菊酯在萝卜叶片中的半衰期为 6.0~6.4 天,消解速度较快。施药后 14 天,萝卜和萝卜叶片中氯氟氰菊酯的中位残留量分别为 0.12 和 3.92mg/kg。膳食摄入风险评估结果表明,中国不同人群氯氟氰菊酯的国家估计日摄入量(NEDI)分别为 0.373 和 5.66μg/(kg bw·d),风险熵(RQ)分别为 0.012 和 0.147,表明氯氟氰菊酯在萝卜中的慢性膳食摄入风险较低。本研究结果为指导氯氟氰菊酯在萝卜生产中的科学使用和评估蔬菜中氯氟氰菊酯的膳食风险提供了数据支持和理论依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93ff/9866042/2ee47be5b3bc/molecules-28-00580-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93ff/9866042/0c9eac4a713c/molecules-28-00580-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93ff/9866042/c708e88e61e7/molecules-28-00580-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93ff/9866042/03414c8fc0e6/molecules-28-00580-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93ff/9866042/2ee47be5b3bc/molecules-28-00580-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93ff/9866042/0c9eac4a713c/molecules-28-00580-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93ff/9866042/c708e88e61e7/molecules-28-00580-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93ff/9866042/03414c8fc0e6/molecules-28-00580-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93ff/9866042/2ee47be5b3bc/molecules-28-00580-g004.jpg

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