2-苯乙胺类化合物在药物化学中的研究进展：综述
2-Phenethylamines in Medicinal Chemistry: A Review.
机构信息
Department of Organic Chemistry, Faculty of Chemical Sciences, University of Salamanca, Pl. Caídos, s/n, 37008 Salamanca, Spain.
出版信息
Molecules. 2023 Jan 14;28(2):855. doi: 10.3390/molecules28020855.
Abstract
A concise review covering updated presence and role of 2-phenethylamines in medicinal chemistry is presented. Open-chain, flexible alicyclic amine derivatives of this motif are enumerated in key therapeutic targets, listing medicinal chemistry hits and appealing screening compounds. Latest reports in discovering new bioactive 2-phenethylamines by research groups are covered too.
摘要
本文简要综述了 2-苯乙胺在药物化学中的存在和作用。列举了该结构的开链、柔性脂环胺衍生物在主要治疗靶点中的应用，列出了药物化学命中物和有吸引力的筛选化合物。还涵盖了研究小组发现新型生物活性 2-苯乙胺的最新报告。
Zotero 插件