Jamaddar Sarmin, Raposo António, Sarkar Chandan, Roy Uttam Kumar, Araújo Isaac Moura, Coutinho Henrique Douglas Melo, Alkhoshaiban Ali Saleh, Alturki Hmidan A, Saraiva Ariana, Carrascosa Conrado, Islam Muhammad Torequl
Department of Pharmacy, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj 8100, Bangladesh.
CBIOS (Research Center for Biosciences and Health Technologies), Universidade Lusófona de Humanidades e Tecnologias, Campo Grande 376, 1749-024 Lisboa, Portugal.
Pharmaceuticals (Basel). 2022 Dec 20;16(1):3. doi: 10.3390/ph16010003.
(Lour.) C. B. Robinson, belonging to the family Lauraceae, is a multipurpose and fast-growing evergreen or deciduous tree that has been traditionally used for numerous purposes such as treatment for diarrhea, dysentery, abdominal pain, indigestion, gastroenteritis, edema, traumatic injuries, colds, arthritis, asthma, diabetes, pain relief, and poignant sexual power. This study aimed to summarize the chemical reports, folk values, and phytopharmacological activities of , based on available information screened from diverse databases. An up-to-date electronic-based search was accomplished to obtain detailed information, with the help of several databases such as Google Scholar, Scopus, SpringerLink, Web of Science, ScienceDirect, ResearchGate, PubMed, ChemSpider, Elsevier, BioMed Central, and the USPTO, CIPO, INPI, Google Patents, and Espacenet, using relevant keywords. Outcomes advocate that, up to the present time, alkaloids, glycosides, and terpenoids are abundant in, and the most bioactive constituents of, this natural plant. Results demonstrated that has various remarkable biological activities, including antioxidant, anti-inflammatory, anti-microbial, anticancer, antipyretic, anti-diabetic, analgesic, hepatoprotective, and wound-healing activity. One study revealed that exhibited significant aphrodisiac and anti-infertility activity. Nevertheless, no clinical studies have been cited. Taken together, may be one of the significant sources of bioactive constituents that could potentially lead to different effective pharmacological activities. On the other hand, future research should focus on clinical studies and several toxicity evaluations, such as sub-chronic toxicity, teratogenicity, and genotoxicity.
(劳尔)C.B. 罗宾逊,属于樟科,是一种多用途且生长迅速的常绿或落叶乔木,传统上被用于多种用途,如治疗腹泻、痢疾、腹痛、消化不良、肠胃炎、水肿、创伤、感冒、关节炎、哮喘、糖尿病、止痛以及增强性功能。本研究旨在基于从不同数据库筛选出的现有信息,总结[植物名称未给出]的化学报告、民间用途和植物药理学活性。借助谷歌学术、Scopus、SpringerLink、科学网、ScienceDirect、ResearchGate、PubMed、ChemSpider、爱思唯尔、生物医学中心以及美国专利商标局、加拿大知识产权局、印度专利局、谷歌专利和欧洲专利局等多个数据库,使用相关关键词,完成了最新的基于电子的搜索以获取详细信息。结果表明,截至目前,生物碱、糖苷和萜类化合物在这种天然植物中含量丰富且是其最具生物活性的成分。结果显示[植物名称未给出]具有多种显著的生物活性,包括抗氧化、抗炎、抗菌、抗癌、解热、抗糖尿病、止痛、保肝和伤口愈合活性。一项研究表明[植物名称未给出]具有显著的壮阳和抗不育活性。然而,尚未引用临床研究。综上所述,[植物名称未给出]可能是生物活性成分的重要来源之一,可能会产生不同的有效药理活性。另一方面,未来的研究应集中在临床研究和一些毒性评估上,如亚慢性毒性、致畸性和遗传毒性。