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耐苯唑西林金黄色葡萄球菌中5型荚膜多糖占优势。

Predominance of capsular polysaccharide type 5 among oxacillin-resistant Staphylococcus aureus.

作者信息

Fournier J M, Bouvet A, Boutonnier A, Audurier A, Goldstein F, Pierre J, Bure A, Lebrun L, Hochkeppel H K

机构信息

Institut Pasteur, Paris, France.

出版信息

J Clin Microbiol. 1987 Oct;25(10):1932-3. doi: 10.1128/jcm.25.10.1932-1933.1987.

DOI:10.1128/jcm.25.10.1932-1933.1987
PMID:3667914
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC269370/
Abstract

The relationship between capsular polysaccharide types 5 and 8 and resistance of Staphylococcus aureus to oxacillin was studied with a collection of 406 clinical isolates from six French hospitals. Of 175 type 5 isolates, 84 (48%) were resistant to oxacillin. In contrast, only 8 of 160 type 8 isolates (5%) and 5 of 71 nontypeable isolates (7%) were resistant to oxacillin. Therefore, capsular typing of clinical isolates of S. aureus may facilitate the choice of first-line antibiotic therapy.

摘要

利用从六家法国医院收集的406株临床分离株，研究了5型和8型荚膜多糖与金黄色葡萄球菌对苯唑西林耐药性之间的关系。在175株5型分离株中，84株（48%）对苯唑西林耐药。相比之下，160株8型分离株中只有8株（5%）以及71株不可分型分离株中有5株（7%）对苯唑西林耐药。因此，对金黄色葡萄球菌临床分离株进行荚膜分型可能有助于一线抗生素治疗的选择。

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本文引用的文献

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[Staphylococcus strains naturally resistant to methicillin and 5-methyl-3-phenyl-4-iso-oxazolyl-penicillin].[对甲氧西林和5-甲基-3-苯基-4-异恶唑基青霉素天然耐药的葡萄球菌菌株]
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Predominance of two newly described capsular polysaccharide types among clinical isolates of Staphylococcus aureus.两种新描述的荚膜多糖类型在金黄色葡萄球菌临床分离株中占主导地位。
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